Protein: BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)

Gene: BACD3, KCTD10
Organism: Homo sapiens
Interactions: 173
UniProt ID: Q9H3F6

Gene Ontology (top 5):
GO:0005112 - Notch binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114281

CUL3
Cullin-3

15

20

Small-scale

0.982

High

1117923

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

7

15

Small-scale

0.967

High

1361867

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

7

15

High-throughput

0.964

High

1432553

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

3

15

Small-scale

0.843

High

1432567

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

5

6

Small-scale

0.718

High

1046419

UBXN1
UBX domain-containing protein 1

4

10

High-throughput

0.694

High

1431382

EPN3
Epsin-3

3

7

High-throughput

0.667

High

1432572

ARI1
E3 ubiquitin-protein ligase ARIH1

3

6

High-throughput

0.667

High

1432557

ADAP2
Arf-GAP with dual PH domain-containing protein 2

3

4

High-throughput

0.657

High

164441

NRP1
Neuropilin-1

2

7

High-throughput

0.628

High

639310

TNAP3
Tumor necrosis factor alpha-induced protein 3

2

6

High-throughput

0.628

High

681926

RBTN2
Rhombotin-2

2

6

High-throughput

0.628

High

850886

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

6

High-throughput

0.628

High

931707

RD23B
UV excision repair protein RAD23 homolog B

2

4

High-throughput

0.628

High

1371191

GLMN
Glomulin

2

1

High-throughput

0.628

High

1432568

RABX5
Rab5 GDP/GTP exchange factor

2

3

High-throughput

0.628

High

1432571

EXOS1
Exosome complex component CSL4

2

1

High-throughput

0.628

High

983973

RBX1
E3 ubiquitin-protein ligase RBX1

2

6

Small-scale

0.611

High

1384264

SH3K1
SH3 domain-containing kinase-binding protein 1

2

13

High-throughput

0.611

High

1150175

TCEA2
Transcription elongation factor A protein 2

2

3

High-throughput

0.606

High

1371435

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

20

High-throughput

0.606

High

1392904

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

9

High-throughput

0.606

High

974281

LSM3
U6 snRNA-associated Sm-like protein LSm3

2

4

High-throughput

0.601

High

508614

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

5

High-throughput

0.595

High

1347455

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.585

High

1432558

ANLN
Anillin

2

1

High-throughput

0.584

High

978299

RHOB
Rho-related GTP-binding protein RhoB

2

9

Small-scale

0.576

High

123830

MYO1C
Unconventional myosin-Ic

1

9

High-throughput

0.536

High

220016

XRCC3
DNA repair protein XRCC3

1

1

High-throughput

0.536

High

221291

DCX
Neuronal migration protein doublecortin

1

2

High-throughput

0.536

High

256506

TOM1
Target of Myb1 membrane trafficking protein

1

4

High-throughput

0.536

High

290728

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

467703

CEL2A
Chymotrypsin-like elastase family member 2A

1

2

High-throughput

0.536

High

637728

FLNA
Filamin-A

1

20

High-throughput

0.536

High

765886

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.536

High

866821

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.536

High

938802

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

10

High-throughput

0.536

High

1142391

PDIA6
Protein disulfide-isomerase A6

1

5

High-throughput

0.536

High

1150485

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

20

High-throughput

0.536

High

1154928

NEDD8
Ubiquitin-like protein NEDD8

1

1

High-throughput

0.536

High

1156327

HSPB2
Heat shock protein beta-2

1

5

High-throughput

0.536

High

1272560

CSN6
COP9 signalosome complex subunit 6

1

4

High-throughput

0.536

High

1370370

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.536

High

1371376

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

9

High-throughput

0.536

High

1391956

DCNL1
DCN1-like protein 1

1

2

High-throughput

0.536

High

1432566

LIMA1
LIM domain and actin-binding protein 1

1

10

High-throughput

0.536

High

927132

ATX3
Ataxin-3

1

0

High-throughput

0.513

High

1210038

LY66F
Lymphocyte antigen 6 complex locus protein G6f

1

0

High-throughput

0.513

High

1432555

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

1

0

High-throughput

0.513

High

605027

HXB6
Homeobox protein Hox-B6

1

6

High-throughput

0.489

High

634884

HXA5
Homeobox protein Hox-A5

1

8

High-throughput

0.489

High

1160756

DREB
Drebrin

1

8

High-throughput

0.489

High

1325118

MTURN
Maturin

1

3

High-throughput

0.489

High

1331790

F133A
Protein FAM133A

1

1

High-throughput

0.489

High

1334171

POC1A
POC1 centriolar protein homolog A

1

8

High-throughput

0.489

High

1365593

MY18A
Unconventional myosin-XVIIIa

1

10

High-throughput

0.489

High

1432573

MB212
Protein mab-21-like 2

1

1

High-throughput

0.489

High

1432564

ITSN2
Intersectin-2

1

11

High-throughput

0.481

High

122550

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

1

Small-scale

0.479

High

125781

STXB3
Syntaxin-binding protein 3

1

4

Small-scale

0.479

High

135347

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

11

Small-scale

0.479

High

157846

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.479

High

187182

PPM1G
Protein phosphatase 1G

1

1

Small-scale

0.479

High

214033

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

Small-scale

0.479

High

214937

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

6

Small-scale

0.479

High

238829

KALRN
Kalirin

1

14

Small-scale

0.479

High

250828

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

Small-scale

0.479

High

255480

SNX2
Sorting nexin-2

1

2

Small-scale

0.479

High

320774

UBXN7
UBX domain-containing protein 7

1

8

High-throughput

0.479

High

329487

EPN2
Epsin-2

1

7

Small-scale

0.479

High

337612

FMNL1
Formin-like protein 1

1

4

Small-scale

0.479

High

348732

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

Small-scale

0.479

High

386226

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

16

Small-scale

0.479

High

417749

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

Small-scale

0.479

High

551256

PCNA
Proliferating cell nuclear antigen

1

3

Small-scale

0.479

High

566215

K1C10
Keratin, type I cytoskeletal 10

1

16

Small-scale

0.479

High

568290

PLST
Plastin-3

1

20

Small-scale

0.479

High

576545

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

5

Small-scale

0.479

High

580835

PVR
Poliovirus receptor

1

6

Small-scale

0.479

High

608746

DDX5
Probable ATP-dependent RNA helicase DDX5

1

4

Small-scale

0.479

High

620586

NUCL
Nucleolin

1

4

Small-scale

0.479

High

634629

LMNB1
Lamin-B1

1

16

Small-scale

0.479

High

662806

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

1

Small-scale

0.479

High

712274

TKT
Transketolase

1

3

Small-scale

0.479

High

715767

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

Small-scale

0.479

High

731610

STIP1
Stress-induced-phosphoprotein 1

1

7

Small-scale

0.479

High

800566

VATA
V-type proton ATPase catalytic subunit A

1

4

Small-scale

0.479

High

857558

NOTC1
Neurogenic locus notch homolog protein 1

1

6

Small-scale

0.479

High

862702

UTRN
Utrophin

1

16

Small-scale

0.479

High

870974

IREB2
Iron-responsive element-binding protein 2

1

1

Small-scale

0.479

High

888560

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

1

Small-scale

0.479

High

900156

FXR1
RNA-binding protein FXR1

1

8

Small-scale

0.479

High

905139

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.479

High

906351

GPC3
Glypican-3

1

1

Small-scale

0.479

High

953098

ACTB
Actin, cytoplasmic 1

1

7

Small-scale

0.479

High

957513

UBC12
NEDD8-conjugating enzyme Ubc12

1

7

High-throughput

0.479

High

959250

ABCE1
ATP-binding cassette sub-family E member 1

1

1

Small-scale

0.479

High

963463

STXB1
Syntaxin-binding protein 1

1

4

Small-scale

0.479

High

996335

EF1A1
Elongation factor 1-alpha 1

1

4

Small-scale

0.479

High

1016226

RL19
Large ribosomal subunit protein eL19

1

1

Small-scale

0.479

High

1035911

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

1039397

RL6
Large ribosomal subunit protein eL6

1

1

Small-scale

0.479

High

1053744

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

7

Small-scale

0.479

High

1058652

CKAP4
Cytoskeleton-associated protein 4

1

14

Small-scale

0.479

High

1111972

SNX1
Sorting nexin-1

1

2

Small-scale

0.479

High

1127159

RBM39
RNA-binding protein 39

1

4

Small-scale

0.479

High

1138051

TNIP1
TNFAIP3-interacting protein 1

1

16

High-throughput

0.479

High

1140847

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

1145525

RBBP5
Retinoblastoma-binding protein 5

1

8

Small-scale

0.479

High

1150818

SF01
Splicing factor 1

1

2

Small-scale

0.479

High

1154508

STXB2
Syntaxin-binding protein 2

1

4

Small-scale

0.479

High

1160295

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

7

Small-scale

0.479

High

1199461

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

8

Small-scale

0.479

High

1227448

A16L1
Autophagy-related protein 16-1

1

16

Small-scale

0.479

High

1270848

SV2A
Synaptic vesicle glycoprotein 2A

1

2

Small-scale

0.479

High

1279306

I2BP2
Interferon regulatory factor 2-binding protein 2

1

7

Small-scale

0.479

High

1280738

YTHD3
YTH domain-containing family protein 3

1

5

Small-scale

0.479

High

1309493

CEP97
Centrosomal protein of 97 kDa

1

15

Small-scale

0.479

High

1324814

KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5

1

2

Small-scale

0.479

High

1347651

NPL4
Nuclear protein localization protein 4 homolog

1

1

Small-scale

0.479

High

1393038

PDLI5
PDZ and LIM domain protein 5

1

7

Small-scale

0.479

High

1393950

FUBP3
Far upstream element-binding protein 3

1

10

Small-scale

0.479

High

1404756

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.479

High

1432554

NELFA
Negative elongation factor A

1

6

Small-scale

0.479

High

1432556

ECT2
Protein ECT2

1

12

High-throughput

0.479

High

1432560

SYFB
Phenylalanine--tRNA ligase beta subunit

1

2

Small-scale

0.479

High

1432563

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

9

Small-scale

0.479

High

1432565

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1432570

FAF1
FAS-associated factor 1

1

9

High-throughput

0.479

High

1432574

YTHD2
YTH domain-containing family protein 2

1

4

Small-scale

0.479

High

1432576

WASF2
Actin-binding protein WASF2

1

6

Small-scale

0.479

High

187796

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

Small-scale

0.458

High

333874

PAPS2
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

1

0

Small-scale

0.458

High

639407

5NTD
5'-nucleotidase

1

0

Small-scale

0.458

High

696483

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

Small-scale

0.458

High

736896

GBP1
Guanylate-binding protein 1

1

0

Small-scale

0.458

High

1111265

SNW1
SNW domain-containing protein 1

1

0

Small-scale

0.458

High

1287585

SETD3
Actin-histidine N-methyltransferase

1

0

Small-scale

0.458

High

1294422

SPAS2
Spermatogenesis-associated serine-rich protein 2

1

0

Small-scale

0.458

High

1307148

TCAM1
TIR domain-containing adapter molecule 1

1

0

Small-scale

0.458

High

1339708

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1356107

SCRB1
Scavenger receptor class B member 1

1

0

Small-scale

0.458

High

1360067

NELFB
Negative elongation factor B

1

0

Small-scale

0.458

High

1361526

CTBL1
Beta-catenin-like protein 1

1

0

Small-scale

0.458

High

1432559

SAS10
Something about silencing protein 10

1

0

Small-scale

0.458

High

1432562

CARF
CDKN2A-interacting protein

1

0

Small-scale

0.458

High

318059

TOM70
Mitochondrial import receptor subunit TOM70

1

6

Small-scale

0.437

High

333764

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

1

3

Small-scale

0.437

High

522498

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

Small-scale

0.437

High

724184

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

Small-scale

0.437

High

1042074

LMNB2
Lamin-B2

1

14

Small-scale

0.437

High

1083204

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

1

Small-scale

0.437

High

1201188

CC157
Coiled-coil domain-containing protein 157

1

20

Small-scale

0.437

High

1278105

MAVS
Mitochondrial antiviral-signaling protein

1

8

Small-scale

0.437

High

1432561

ATD3A
ATPase family AAA domain-containing protein 3A

1

7

Small-scale

0.437

High

1432575

PCLO
Protein piccolo

1

14

Small-scale

0.437

High

1187333

CMA1D
Protein CIMAP1D

2

0

High-throughput

0.328

High

1251841

PPR21
Protein phosphatase 1 regulatory subunit 21

2

0

High-throughput

0.328

High

1391370

CFA36
Cilia- and flagella-associated protein 36

2

0

High-throughput

0.328

High

1410449

SOST
Sclerostin

2

0

High-throughput

0.328

High

1314992

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.316

High

128585

AGRP
Agouti-related protein

1

0

High-throughput

0.279

Low

569274

YJU2B
Probable splicing factor YJU2B

1

0

High-throughput

0.279

Low

889937

VEGFB
Vascular endothelial growth factor B

1

0

High-throughput

0.279

Low

1410524

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1432569

TBX20
T-box transcription factor TBX20

1

0

High-throughput

0.279

Low

423847

APOD
Apolipoprotein D

1

0

Small-scale

0.249

Low

571517

GLU2B
Glucosidase 2 subunit beta

1

0

Small-scale

0.249

Low

863553

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

0

Small-scale

0.249

Low

1362112

IRGQ
Immunity-related GTPase family Q protein

1

0

Small-scale

0.249

Low

1415040

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

Small-scale

0.249

Low

1415538

GNL3
Guanine nucleotide-binding protein-like 3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025