HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21858095
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 579 Hs			1 1922
+	Hs
		1349173 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		1072067 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		1283869 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		1357794 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		1294281 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		1031498 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		1273100 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Hs
		516748 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		DICER_HUMAN (1-1922): 0: 1763: 100.00
+	Ce
		712188 HRPK1_CAEEL (160-566): 1.07e-70: 234: 18.54		DCR1_CAEEL (42-1918): 0: 1083: 30.31
+	Ce
		712205 Q21605_CAEEL (172-559): 2.02e-65: 230: 24.79		DCR1_CAEEL (42-1918): 0: 1083: 30.31
+	Hs
		128019 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		DDX5_HUMAN (6-364): 3.03e-66: 239: 11.54
+	Hs
		571615 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		DDX5_HUMAN (6-364): 3.03e-66: 239: 11.54
+	Hs
		1071998 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		IFIH1_HUMAN (33-641): 7.5e-85: 304: 19.44
+	Hs
		1072175 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		IFIH1_HUMAN (33-641): 7.5e-85: 304: 19.44
+	Hs
		321901 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		RIGI_HUMAN (34-641): 5.74e-79: 284: 19.97
+	Hs
		321902 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		RIGI_HUMAN (34-641): 5.74e-79: 284: 19.97
+	Hs
		571464 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		DDX5_HUMAN (6-364): 3.03e-66: 239: 11.54
+	Hs
		516391 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		IF4A3_HUMAN (6-251): 1.27e-52: 193: 11.37
+	Hs
		516589 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		ASCC3_HUMAN (13-493): 5.92e-31: 136: 11.18
+	Hs
		1273081 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		RNC_HUMAN (1311-1374): 1.17e-12: 75.8: 32.81