HitPredict

Interactor 1: ARRD3 (Q96B67)
Arrestin domain-containing protein 3 (TBP-2-like inducible membrane protein) (TLIMP)
Gene: ARRDC3

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33722977
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 414 Hs			1 400
+	Hs
		808830 ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1285070 ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1285047 ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		125633 ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1252814 ARRD2_HUMAN (1-411): 3.62e-128: 377: 53.16		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1252807 ARRD2_HUMAN (1-411): 3.62e-128: 377: 53.16		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		1241917 ARRD4_HUMAN (4-411): 1.8e-123: 365: 51.10		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		125595 ARRD2_HUMAN (1-411): 3.62e-128: 377: 53.16		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1241904 ARRD4_HUMAN (4-411): 1.8e-123: 365: 51.10		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		125586 ARRD4_HUMAN (4-411): 1.8e-123: 365: 51.10		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1327911 TXNIP_HUMAN (1-399): 5.09e-112: 335: 40.75		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1294858 TXNIP_HUMAN (1-399): 5.09e-112: 335: 40.75		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		125707 TXNIP_HUMAN (1-399): 5.09e-112: 335: 40.75		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		808216 ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		1285083 ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1285052 ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		1252808 ARRD2_HUMAN (1-411): 3.62e-128: 377: 53.16		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		1330179 TXNIP_HUMAN (1-399): 5.09e-112: 335: 40.75		SMUF2_HUMAN (156-326): 4.16e-25: 109: 11.92
+	Hs
		1241907 ARRD4_HUMAN (4-411): 1.8e-123: 365: 51.10		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		1299631 TXNIP_HUMAN (1-399): 5.09e-112: 335: 40.75		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20