HitPredict

Interactor 1: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1343 Hs			1 197
+	Mm
		100069 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG2_MOUSE (23-196): 1.12e-25: 105: 23.63
+	Mm
		99993 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		942370 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Mm
		100035 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG1_MOUSE (50-178): 1.33e-22: 96.3: 30.60
+	Mm
		99954 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG3_MOUSE (60-164): 3.31e-21: 92.5: 32.73
+	Hs
		1271022 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		DLG3_HUMAN (74-164): 2.8e-20: 89.8: 35.42
+	Hs
		1252417 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Rn
		677806 SYGP1_RAT (1-1301): 0: 976: 98.85		DLG4_RAT (59-195): 2.17e-23: 98.7: 26.76
+	Rn
		1144081 SYGP1_RAT (1-1301): 0: 976: 98.85		DLG3_RAT (60-164): 3.16e-21: 92.5: 32.73
+	Mm
		1112545 DAB2P_MOUSE (97-1342): 0: 771: 46.89		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		1296951 NGAP_HUMAN (84-1341): 0: 732: 42.62		SNX27_HUMAN (91-175): 2.59e-12: 66.6: 38.14
+	Hs
		1300689 NGAP_HUMAN (84-1341): 0: 732: 42.62		MAGI1_HUMAN (94-172): 5.41e-10: 60.1: 35.44
+	Mm
		1113181 IQGA2_MOUSE (216-848): 2.25e-120: 413: 13.94		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		809371 IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Mm
		1143561 RASL1_MOUSE (162-680): 4.92e-119: 392: 19.93		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		809403 IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21		MAGI1_HUMAN (94-172): 5.41e-10: 60.1: 35.44
+	Hs
		598468 NF1_HUMAN (408-712): 3.21e-82: 301: 23.21		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		598514 NF1_HUMAN (408-712): 3.21e-82: 301: 23.21		MAGI1_HUMAN (94-172): 5.41e-10: 60.1: 35.44