Interactor 1: OTUL (Q96BN8)
Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby)
Gene: OTULIN

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 26670046, 28189684, 27458237, 27307491, 27545878, 33329596, 36640323, 23708998, 24726327, 24726323, 27591049, 28244869, 28919039, 31541095, 31504727, 34545182, 35939695, 36398858, 37589075
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, unspecified method, two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0071797 - LUBAC complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 352
Hs

1 1072
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024