Interactor 1: ISCA2 (Q86U28)
Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1)
Gene: ISCA2
Interactor 2: ISCA1 (Q9BUE6)
Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (hIscA)
Gene: ISCA1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.71 | 1.00 | 0.847 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 25347204, unassigned3799 |
| Identification Methods | affinity chromatography technology, nuclear magnetic resonance, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Fe-S_biosyn~Fe-S_biosyn |
| Common GO terms | GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0016226 - iron-sulfur cluster assembly GO:0051537 - 2 iron, 2 sulfur cluster binding GO:0120510 - mitochondrial [4Fe-4S] assembly complex |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
