HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SEPT9 (Q9UHD8)
Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1)
Gene: SEPTIN9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0015630 - microtubule cytoskeleton
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 586
+	Hs
		198179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEPT4_HUMAN (195-569): 0: 558: 44.30
+	Hs
		497495 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEPT5_HUMAN (262-574): 1.48e-178: 510: 46.03
+	Hs
		497039 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEPT2_HUMAN (260-580): 7.56e-177: 506: 45.68
+	Hs
		497093 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEPT7_HUMAN (277-584): 3.95e-172: 496: 48.05
+	Hs
		497740 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEPT3_HUMAN (254-568): 1.51e-167: 482: 67.49
+	Hs
		497668 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEP11_HUMAN (265-583): 1.9e-165: 479: 39.06
+	Hs
		90135 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		D6RGI3_HUMAN (265-583): 2.72e-165: 479: 39.06
+	Hs
		497368 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEPT8_HUMAN (266-584): 3.09e-164: 478: 39.38
+	Hs
		496998 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEPT6_HUMAN (277-583): 5.85e-163: 473: 41.56
+	Rn
		582045 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SEPT7_RAT (277-584): 7.5e-172: 496: 48.05
+	Rn
		94268 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SEPT7_RAT (277-584): 7.5e-172: 496: 48.05
+	Mm
		498090 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		SEPT8_MOUSE (266-584): 1.4e-164: 477: 39.38
+	Mm
		498157 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		SEPT6_MOUSE (277-583): 1.57e-162: 472: 41.56
+	Hs
		152655 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		SEPT7_HUMAN (277-584): 3.95e-172: 496: 48.05