Interactor 1: ORAI1 (Q96D31)
Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)
Gene: ORAI1

Interactor 2: ORAI3 (Q9BRQ5)
Protein orai-3 (Transmembrane protein 142C)
Gene: ORAI3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 19887627, 24954132
Identification Methods fluorescent resonance energy transfer, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Orai-1~Orai-1
Common GO terms GO:0002115 - store-operated calcium entry
GO:0005886 - plasma membrane
GO:0015279 - store-operated calcium channel activity
GO:0016020 - membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 301
Hs

1 295
+ Hs
+ Dm

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Last updated: 15 Jul 2024