Interactor 1: ORAI1 (Q96D31)
Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)
Gene: ORAI1

Interactor 2: EFC4B (Q9BSW2)
EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46)
Gene: CRACR2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.569

The method score is based on:

Property Details
Experiments 20418871
Identification Methods anti tag coimmunoprecipitation, pull down
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002115 - store-operated calcium entry
GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0051928 - positive regulation of calcium ion transport
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 301
Hs

1 731
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024