Protein: APJ
Apelin receptor (Angiotensin receptor-like 1) (G-protein coupled receptor APJ) (G-protein coupled receptor HG11)

Gene: APJ, APLNR
Organism: Homo sapiens
Interactions: 214
UniProt ID: P35414

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001568 - blood vessel development
GO:0001570 - vasculogenesis
GO:0001944 - vasculature development
GO:0001947 - heart looping

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

674830

AGTR1
Type-1 angiotensin II receptor

2

16

Small-scale

0.789

High

723278

OPRK
Kappa-type opioid receptor

2

18

Small-scale

0.754

High

708264

TTK
Dual specificity protein kinase TTK

2

4

High-throughput

0.726

High

723281

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

2

High-throughput

0.691

High

723275

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.656

High

126771

ACATN
Acetyl-coenzyme A transporter 1

2

2

High-throughput

0.628

High

168170

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

2

5

High-throughput

0.628

High

255294

HIP1R
Huntingtin-interacting protein 1-related protein

2

3

High-throughput

0.628

High

392653

B3A2
Anion exchange protein 2

2

3

High-throughput

0.628

High

591515

RAB3B
Ras-related protein Rab-3B

2

3

High-throughput

0.628

High

616748

JAK1
Tyrosine-protein kinase JAK1

2

18

High-throughput

0.628

High

619204

AT2B4
Plasma membrane calcium-transporting ATPase 4

2

20

High-throughput

0.628

High

723290

ARF5
ADP-ribosylation factor 5

2

2

High-throughput

0.628

High

723309

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

2

9

High-throughput

0.628

High

723320

AB17B
Alpha/beta hydrolase domain-containing protein 17B

2

8

High-throughput

0.628

High

723352

T161B
Transmembrane protein 161B

2

4

High-throughput

0.628

High

723353

MCU
Calcium uniporter protein, mitochondrial

2

3

High-throughput

0.628

High

723357

EXOC6
Exocyst complex component 6

2

3

High-throughput

0.628

High

723365

EDA
Ectodysplasin-A

2

1

High-throughput

0.628

High

723368

EXOC4
Exocyst complex component 4

2

3

High-throughput

0.628

High

723373

COQ8B
Atypical kinase COQ8B, mitochondrial

2

7

High-throughput

0.628

High

723380

EXOC2
Exocyst complex component 2

2

4

High-throughput

0.628

High

723388

S29A1
Equilibrative nucleoside transporter 1

2

3

High-throughput

0.628

High

723392

NDC1
Nucleoporin NDC1

2

1

High-throughput

0.628

High

723417

EXOC1
Exocyst complex component 1

2

2

High-throughput

0.628

High

723427

S53A1
Solute carrier family 53 member 1

2

1

High-throughput

0.628

High

723386

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

1

High-throughput

0.618

High

208442

OX1R
Orexin/Hypocretin receptor type 1

1

18

Small-scale

0.618

High

661147

CXB2
Gap junction beta-2 protein

2

8

High-throughput

0.606

High

723351

DGLB
Diacylglycerol lipase-beta

2

0

High-throughput

0.602

High

723374

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

2

0

High-throughput

0.602

High

685813

ARRB2
Beta-arrestin-2

1

13

Small-scale

0.590

High

723381

MARK4
MAP/microtubule affinity-regulating kinase 4

1

0

High-throughput

0.584

High

723360

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.578

High

63302

MET15
12S rRNA N4-methylcytidine

2

2

High-throughput

0.574

High

162445

XPO1
Exportin-1

2

17

High-throughput

0.574

High

163574

BTAF1
TATA-binding protein-associated factor 172

2

5

High-throughput

0.574

High

176563

FANCA
Fanconi anemia group A protein

2

3

High-throughput

0.574

High

217238

ORC5
Origin recognition complex subunit 5

2

2

High-throughput

0.574

High

298212

UFL1
E3 UFM1-protein ligase 1

2

2

High-throughput

0.574

High

335661

COX1
Cytochrome c oxidase subunit 1

2

2

High-throughput

0.574

High

490051

NR2F6
Nuclear receptor subfamily 2 group F member 6

2

5

High-throughput

0.574

High

573596

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

7

High-throughput

0.574

High

622768

COT2
COUP transcription factor 2

2

5

High-throughput

0.574

High

708086

ABCD1
ATP-binding cassette sub-family D member 1

2

3

High-throughput

0.574

High

723283

AK1D1
Aldo-keto reductase family 1 member D1

2

3

High-throughput

0.574

High

723291

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

2

3

High-throughput

0.574

High

723297

MTX1
Metaxin-1

2

5

High-throughput

0.574

High

723300

COG2
Conserved oligomeric Golgi complex subunit 2

2

2

High-throughput

0.574

High

723310

D19L1
Protein C-mannosyl-transferase DPY19L1

2

1

High-throughput

0.574

High

723313

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

2

9

High-throughput

0.574

High

723315

MTX3
Metaxin-3

2

5

High-throughput

0.574

High

723318

TM164
Transmembrane protein 164

2

2

High-throughput

0.574

High

723321

ECM29
Proteasome adapter and scaffold protein ECM29

2

9

High-throughput

0.574

High

723322

ATLA3
Atlastin-3

2

7

High-throughput

0.574

High

723323

ACD10
Acyl-CoA dehydrogenase family member 10

2

3

High-throughput

0.574

High

723325

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

2

10

High-throughput

0.574

High

723326

RINT1
RAD50-interacting protein 1

2

5

High-throughput

0.574

High

723327

TTI2
TELO2-interacting protein 2

2

2

High-throughput

0.574

High

723328

MZT2B
Mitotic-spindle organizing protein 2B

2

3

High-throughput

0.574

High

723330

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

2

4

High-throughput

0.574

High

723332

BRAT1
BRCA1-associated ATM activator 1

2

2

High-throughput

0.574

High

723333

HACD2
Very-long-chain

2

2

High-throughput

0.574

High

723334

THADA
tRNA

2

4

High-throughput

0.574

High

723338

ADCK1
AarF domain-containing protein kinase 1

2

7

High-throughput

0.574

High

723341

DAAF5
Dynein axonemal assembly factor 5

2

4

High-throughput

0.574

High

723342

T126B
Complex I assembly factor TMEM126B, mitochondrial

2

3

High-throughput

0.574

High

723344

INT1
Integrator complex subunit 1

2

6

High-throughput

0.574

High

723350

MFSD9
Major facilitator superfamily domain-containing protein 9

2

6

High-throughput

0.574

High

723359

SFXN5
Sideroflexin-5

2

6

High-throughput

0.574

High

723369

S2546
Mitochondrial outer membrane protein SLC25A46

2

4

High-throughput

0.574

High

723370

INT12
Integrator complex subunit 12

2

3

High-throughput

0.574

High

723371

GCP3
Gamma-tubulin complex component 3

2

11

High-throughput

0.574

High

723393

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

2

10

High-throughput

0.574

High

723401

INT2
Integrator complex subunit 2

2

2

High-throughput

0.574

High

723402

ARV1
Protein ARV1

2

1

High-throughput

0.574

High

723413

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

10

High-throughput

0.574

High

723416

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

2

7

High-throughput

0.574

High

723419

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

2

2

High-throughput

0.574

High

723421

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

2

3

High-throughput

0.574

High

723424

ELOV5
Very long chain fatty acid elongase 5

2

4

High-throughput

0.574

High

723428

CS025
UPF0449 protein C19orf25

2

1

High-throughput

0.574

High

723429

GCP4
Gamma-tubulin complex component 4

2

11

High-throughput

0.574

High

723430

IPO11
Importin-11

2

11

High-throughput

0.574

High

723431

XPO7
Exportin-7

2

18

High-throughput

0.574

High

723436

DOLK
Dolichol kinase

2

3

High-throughput

0.574

High

723437

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

2

3

High-throughput

0.574

High

723439

ZDHC9
Palmitoyltransferase ZDHHC9

2

1

High-throughput

0.574

High

723441

PEX16
Peroxisomal membrane protein PEX16

2

2

High-throughput

0.574

High

723303

PDK1
[Pyruvate dehydrogenase

2

3

High-throughput

0.558

High

723284

SC5A3
Sodium/myo-inositol cotransporter

2

2

High-throughput

0.552

High

527321

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.541

High

723434

NDRG4
Protein NDRG4

1

4

High-throughput

0.541

High

160909

RAB7L
Ras-related protein Rab-7L1

1

3

High-throughput

0.536

High

168241

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

3

High-throughput

0.536

High

314960

SGPL1
Sphingosine-1-phosphate lyase 1

1

1

High-throughput

0.536

High

518096

ADT1
ADP/ATP translocase 1

1

9

High-throughput

0.536

High

572298

LEG3
Galectin-3

1

3

High-throughput

0.536

High

723282

RAB13
Ras-related protein Rab-13

1

1

High-throughput

0.536

High

723285

AT12A
Potassium-transporting ATPase alpha chain 2

1

19

High-throughput

0.536

High

723286

S12A2
Solute carrier family 12 member 2

1

4

High-throughput

0.536

High

723289

RAB38
Ras-related protein Rab-38

1

4

High-throughput

0.536

High

723292

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

4

High-throughput

0.536

High

723296

ATM
Serine-protein kinase ATM

1

14

High-throughput

0.536

High

723306

MSMO1
Methylsterol monooxygenase 1

1

2

High-throughput

0.536

High

723319

RIF1
Telomere-associated protein RIF1

1

3

High-throughput

0.536

High

723345

NIN
Ninein

1

4

High-throughput

0.536

High

723347

MIGA1
Mitoguardin 1

1

2

High-throughput

0.536

High

723349

TM87A
Transmembrane protein 87A

1

4

High-throughput

0.536

High

723366

GLMN
Glomulin

1

1

High-throughput

0.536

High

723377

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

8

High-throughput

0.536

High

723390

GCP2
Gamma-tubulin complex component 2

1

11

High-throughput

0.536

High

723398

YIPF3
Protein YIPF3

1

4

High-throughput

0.536

High

723400

T126A
Transmembrane protein 126A

1

3

High-throughput

0.536

High

723409

RAB18
Ras-related protein Rab-18

1

4

High-throughput

0.536

High

723423

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

3

High-throughput

0.536

High

723425

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

4

High-throughput

0.536

High

723432

AMFR
E3 ubiquitin-protein ligase AMFR

1

3

High-throughput

0.536

High

723288

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

723295

FOXF1
Forkhead box protein F1

1

0

High-throughput

0.513

High

723307

TAZ
Tafazzin

1

0

High-throughput

0.513

High

723375

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

544730

ALDR
Aldo-keto reductase family 1 member B1

1

3

High-throughput

0.494

High

723426

MTCH1
Mitochondrial carrier homolog 1

1

12

High-throughput

0.494

High

178120

IPO8
Importin-8

1

10

High-throughput

0.489

High

199284

ZW10
Centromere/kinetochore protein zw10 homolog

1

3

High-throughput

0.489

High

313064

AGM1
Phosphoacetylglucosamine mutase

1

1

High-throughput

0.489

High

474456

GPHRB
Golgi pH regulator B

1

8

High-throughput

0.489

High

622652

ERD21
ER lumen protein-retaining receptor 1

1

2

High-throughput

0.489

High

702606

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

2

High-throughput

0.489

High

723276

FDFT
Squalene synthase

1

1

High-throughput

0.489

High

723277

VKGC
Vitamin K-dependent gamma-carboxylase

1

1

High-throughput

0.489

High

723279

MTOR
Serine/threonine-protein kinase mTOR

1

16

High-throughput

0.489

High

723287

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.489

High

723293

TAP1
Antigen peptide transporter 1

1

3

High-throughput

0.489

High

723298

TBB3
Tubulin beta-3 chain

1

5

High-throughput

0.489

High

723299

URB2
Unhealthy ribosome biogenesis protein 2 homolog

1

1

High-throughput

0.489

High

723301

DPOD3
DNA polymerase delta subunit 3

1

1

High-throughput

0.489

High

723302

OXA1L
Mitochondrial inner membrane protein OXA1L

1

2

High-throughput

0.489

High

723304

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

1

High-throughput

0.489

High

723305

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.489

High

723311

TBB8
Tubulin beta-8 chain

1

5

High-throughput

0.489

High

723314

PIGG
GPI ethanolamine phosphate transferase 2

1

6

High-throughput

0.489

High

723316

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

2

High-throughput

0.489

High

723317

TM201
Transmembrane protein 201

1

1

High-throughput

0.489

High

723324

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

11

High-throughput

0.489

High

723329

SFXN4
Sideroflexin-4

1

6

High-throughput

0.489

High

723331

INT5
Integrator complex subunit 5

1

2

High-throughput

0.489

High

723335

CERS6
Ceramide synthase 6

1

13

High-throughput

0.489

High

723336

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

9

High-throughput

0.489

High

723339

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

4

High-throughput

0.489

High

723340

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

14

High-throughput

0.489

High

723343

MIRO2
Mitochondrial Rho GTPase 2

1

15

High-throughput

0.489

High

723348

UBAC2
Ubiquitin-associated domain-containing protein 2

1

1

High-throughput

0.489

High

723354

NAV1
Neuron navigator 1

1

4

High-throughput

0.489

High

723356

ATLA2
Atlastin-2

1

7

High-throughput

0.489

High

723358

S2540
Mitochondrial glutathione transporter SLC25A40

1

14

High-throughput

0.489

High

723361

PIGO
GPI ethanolamine phosphate transferase 3

1

6

High-throughput

0.489

High

723362

CHPT1
Cholinephosphotransferase 1

1

4

High-throughput

0.489

High

723364

TM9S4
Transmembrane 9 superfamily member 4

1

7

High-throughput

0.489

High

723372

F241B
Protein FAM241B

1

2

High-throughput

0.489

High

723376

RUSF1
RUS family member 1

1

1

High-throughput

0.489

High

723378

MYO19
Unconventional myosin-XIX

1

2

High-throughput

0.489

High

723379

VPS50
Syndetin

1

2

High-throughput

0.489

High

723382

MBOA7
Lysophospholipid acyltransferase 7

1

9

High-throughput

0.489

High

723384

CP2S1
Cytochrome P450 2S1

1

1

High-throughput

0.489

High

723387

SGMR1
Sigma non-opioid intracellular receptor 1

1

5

High-throughput

0.489

High

723391

S2533
Solute carrier family 25 member 33

1

11

High-throughput

0.489

High

723394

PTSS2
Phosphatidylserine synthase 2

1

4

High-throughput

0.489

High

723395

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

1

High-throughput

0.489

High

723396

SFXN3
Sideroflexin-3

1

6

High-throughput

0.489

High

723397

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.489

High

723399

DERL2
Derlin-2

1

3

High-throughput

0.489

High

723404

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

1

High-throughput

0.489

High

723405

SFXN1
Sideroflexin-1

1

6

High-throughput

0.489

High

723406

COG4
Conserved oligomeric Golgi complex subunit 4

1

2

High-throughput

0.489

High

723407

XPO5
Exportin-5

1

16

High-throughput

0.489

High

723408

TPC
Mitochondrial thiamine pyrophosphate carrier

1

11

High-throughput

0.489

High

723414

ECHD1
Ethylmalonyl-CoA decarboxylase

1

3

High-throughput

0.489

High

723415

MDN1
Midasin

1

3

High-throughput

0.489

High

723418

DJC11
DnaJ homolog subfamily C member 11

1

4

High-throughput

0.489

High

723433

KDIS
Kinase D-interacting substrate of 220 kDa

1

1

High-throughput

0.489

High

723435

TMCO1
Calcium load-activated calcium channel

1

4

High-throughput

0.489

High

723438

CDYL
Chromodomain Y-like protein

1

2

High-throughput

0.489

High

723442

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

4

High-throughput

0.489

High

723312

Q4LE69
1-phosphatidylinositol 4-kinase

1

6

High-throughput

0.479

High

723280

PI4KA
Phosphatidylinositol 4-kinase alpha

1

8

High-throughput

0.445

High

81549

B7Z207
Protein-serine/threonine kinase

1

3

High-throughput

0.407

High

181951

OGG1
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase

2

0

High-throughput

0.328

High

371067

NU1M
NADH-ubiquinone oxidoreductase chain 1

2

0

High-throughput

0.328

High

686156

GLPK
Glycerol kinase

2

0

High-throughput

0.328

High

723294

ABD18
Protein ABHD18

2

0

High-throughput

0.328

High

723337

SETD3
Actin-histidine N-methyltransferase

1

0

High-throughput

0.282

High

123369

GET1
Guided entry of tail-anchored proteins factor 1

1

0

High-throughput

0.279

Low

157539

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.279

Low

207021

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.279

Low

260181

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.279

Low

296545

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

0

High-throughput

0.279

Low

620661

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

723308

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.279

Low

723346

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.279

Low

723363

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

723367

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.279

Low

723383

TM209
Transmembrane protein 209

1

0

High-throughput

0.279

Low

723385

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.279

Low

723389

MIC25
MICOS complex subunit MIC25

1

0

High-throughput

0.279

Low

723410

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.279

Low

723411

PYRG2
CTP synthase 2

1

0

High-throughput

0.279

Low

723412

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

High-throughput

0.279

Low

723420

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.279

Low

723422

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

1

0

High-throughput

0.279

Low

723440

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.279

Low

723403

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

723355

TOIP2
Torsin-1A-interacting protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024