Interactor 1: NOXA1 (Q86UR1)
NADPH oxidase activator 1 (NOX activator 1) (Antigen NY-CO-31) (NCF2-like protein) (P67phox-like factor) (p51-nox)
Gene: NOXA1

Interactor 2: NOXO1 (Q8NFA2)
NADPH oxidase organizer 1 (NADPH oxidase regulatory protein) (Nox organizer 1) (Nox-organizing protein 1) (SH3 and PX domain-containing protein 5)
Gene: NOXO1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 39426288, 20110267, 35031518, 17126813, 23957209
Identification Methods proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~SH3_1, SH3_1~SH3_1
Common GO terms GO:0010310 - regulation of hydrogen peroxide metabolic process
GO:0016176 - superoxide-generating NADPH oxidase activator activity
GO:0019899 - enzyme binding
GO:0042554 - superoxide anion generation
GO:0043020 - NADPH oxidase complex
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 476
Hs

1 376
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025