Protein: NOXA1
NADPH oxidase activator 1 (NOX activator 1) (Antigen NY-CO-31) (NCF2-like protein) (P67phox-like factor) (p51-nox)

Gene: NOXA1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q86UR1

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006801 - superoxide metabolic process
GO:0010310 - regulation of hydrogen peroxide metabolic process
GO:0016176 - superoxide-generating NADPH oxidase activator activity
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1288875

NOXO1
NADPH oxidase organizer 1

5

4

Small-scale

0.909

High

1288886

RIM3A
RIMS-binding protein 3A

3

1

High-throughput

0.776

High

1288869

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.742

High

703636

MK01
Mitogen-activated protein kinase 1

1

1

Small-scale

0.710

High

424666

KPCG
Protein kinase C gamma type

1

3

High-throughput

0.656

High

1186109

ANR55
Ankyrin repeat domain-containing protein 55

2

0

High-throughput

0.655

High

603301

KPCA
Protein kinase C alpha type

1

3

Small-scale

0.647

High

605738

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

Small-scale

0.647

High

1153370

MK11
Mitogen-activated protein kinase 11

1

2

Small-scale

0.647

High

572839

NCF1
Neutrophil cytosol factor 1

1

4

Small-scale

0.621

High

1090755

TRAF2
TNF receptor-associated factor 2

2

1

High-throughput

0.606

High

1186954

KR151
Keratin-associated protein 15-1

2

1

High-throughput

0.606

High

1288888

NOX1
NADPH oxidase 1

2

2

Small-scale

0.595

High

833651

NAA10
N-alpha-acetyltransferase 10

2

0

High-throughput

0.589

High

1288872

HACE1
E3 ubiquitin-protein ligase HACE1

1

0

Small-scale

0.586

High

868201

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.580

High

1048898

REL
Proto-oncogene c-Rel

2

0

High-throughput

0.580

High

1119748

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

2

0

High-throughput

0.580

High

1186930

KR194
Keratin-associated protein 19-4

2

0

High-throughput

0.580

High

1187883

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.580

High

1200181

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

2

0

High-throughput

0.580

High

1233233

NADE
Glutamine-dependent NAD(+) synthetase

2

0

High-throughput

0.580

High

1288871

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.580

High

1288874

SMIP6
Sperm microtubule inner protein 6

2

0

High-throughput

0.580

High

1288876

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.580

High

1288878

MYLIP
E3 ubiquitin-protein ligase MYLIP

2

0

High-throughput

0.580

High

1288880

TGS1
Trimethylguanosine synthase

2

0

High-throughput

0.580

High

1288882

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

651680

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

2

Small-scale

0.575

High

1158130

MK14
Mitogen-activated protein kinase 14

1

2

Small-scale

0.575

High

66399

RIM3C
RIMS-binding protein 3C

1

1

High-throughput

0.555

High

1067475

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.481

High

1288870

KR131
Keratin-associated protein 13-1

1

1

High-throughput

0.481

High

988493

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

Small-scale

0.479

High

1226984

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1270881

RHOU
Rho-related GTP-binding protein RhoU

1

4

Small-scale

0.479

High

1127573

FAT1
Protocadherin Fat 1

1

0

Small-scale

0.460

High

1288879

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.458

High

990429

1433Z
14-3-3 protein zeta/delta

1

0

Small-scale

0.426

High

70317

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

156469

ACPM
Acyl carrier protein, mitochondrial

2

0

High-throughput

0.316

High

192109

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

350302

DDAH2
Putative hydrolase DDAH2

2

0

High-throughput

0.316

High

437465

CRBA1
Beta-crystallin A3 [Cleaved into: Beta-crystallin A3, isoform A1, Delta4 form; Beta-crystallin A3, isoform A1, Delta7 form; Beta-crystallin A3, isoform A1, Delta8 form]

2

0

High-throughput

0.316

High

587130

ITF2
Transcription factor 4

2

0

High-throughput

0.316

High

681855

RBTN2
Rhombotin-2

2

0

High-throughput

0.316

High

699463

PROP
Properdin

2

0

High-throughput

0.316

High

783311

TRI23
E3 ubiquitin-protein ligase TRIM23

2

0

High-throughput

0.316

High

1095033

DUS4
Dual specificity protein phosphatase 4

2

0

High-throughput

0.316

High

1133113

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.316

High

1198815

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

0

High-throughput

0.316

High

1203475

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

1213498

UBAP2
Ubiquitin-associated protein 2

2

0

High-throughput

0.316

High

1244196

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.316

High

1247547

ZN474
Zinc finger protein 474

2

0

High-throughput

0.316

High

1253056

ZN620
Zinc finger protein 620

2

0

High-throughput

0.316

High

1288873

MET27
Methyltransferase-like protein 27

2

0

High-throughput

0.316

High

1288877

P66B
Transcriptional repressor p66-beta

2

0

High-throughput

0.316

High

1288881

KCD15
BTB/POZ domain-containing protein KCTD15

2

0

High-throughput

0.316

High

1288883

WDR83
WD repeat domain-containing protein 83

2

0

High-throughput

0.316

High

1288884

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

2

0

High-throughput

0.316

High

1288885

DCR1B
5' exonuclease Apollo

2

0

High-throughput

0.316

High

1288887

TCF19
Transcription factor 19

2

0

High-throughput

0.316

High

139721

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.265

Low

1272640

DET1
DET1 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025