Interactor 1: MTMR8 (Q96EF0)
Myotubularin-related protein 8 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)
Gene: MTMR8

Interactor 2: MTMR9 (Q96QG7)
Myotubularin-related protein 9 (Inactive phosphatidylinositol 3-phosphatase 9)
Gene: MTMR9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 16189514, 27880917, 27432908, 25659891, 28514442, 29892012, 33961781, 22647598, 31515488
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myotub-related~Myotub-related
Common GO terms GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010507 - negative regulation of autophagy
GO:0032991 - protein-containing complex
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 704
Hs

1 549
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Last updated: 15 Jul 2024