HitPredict

Interactor 1: OTUB1 (Q96FW1)
Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1)
Gene: OTUB1

Interactor 2: HIF1N (Q9NWT6)
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase)
Gene: HIF1AN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.55 0.715

The method score is based on:

Property Details
Experiments 26752685, 28514442, 26972000, 31299612, 33961781, 24145445, unassigned1260
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, hydroxylase assay
Interaction Type physical association, association, hydroxylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 0

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Last updated: 15 Jul 2024