HitPredict

Interactor 1: RN185 (Q96GF1)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: RNF185

Interactor 2: TMUB1 (Q9BVT8)
Transmembrane and ubiquitin-like domain-containing protein 1 (Dendritic cell-derived ubiquitin-like protein) (DULP) (Hepatocyte odd protein shuttling protein) (Ubiquitin-like protein SB144) [Cleaved into: iHOPS]
Gene: TMUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.886

Property	Details
Experiments	32738194, 32614325, 33961781, 35961308
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0036503 - ERAD pathway
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 246
+	Hs
		1307257 RNF5_HUMAN (15-173): 2.18e-37: 129: 60.38		TMUB1_HUMAN (1-246): 1.04e-141: 398: 100.00
+	Hs
		1295770 RN170_HUMAN (26-191): 1.11e-28: 109: 18.64		TMUB1_HUMAN (1-246): 1.04e-141: 398: 100.00
+	Hs
		1314264 AMFR_HUMAN (27-171): 2.12e-24: 101: 19.18		TMUB1_HUMAN (1-246): 1.04e-141: 398: 100.00
+	Hs
		1174918 RN185_HUMAN (1-192): 2.35e-56: 178: 100.00		TMUB2_HUMAN (1-244): 1.02e-105: 310: 38.10
+	Hs
		1174921 RNF5_HUMAN (15-173): 2.18e-37: 129: 60.38		TMUB2_HUMAN (1-244): 1.02e-105: 310: 38.10