HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: GOGA2 (Q08379)
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)
Gene: GOLGA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015031 - protein transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 1002
+	Hs
		129221 P85B_HUMAN (1-728): 0: 549: 100.00		MYH10_HUMAN (449-991): 1.35e-23: 110: 9.74
+	Hs
		129220 P85B_HUMAN (1-728): 0: 549: 100.00		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		411692 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		GOGA2_HUMAN (1-1002): 2.79e-77: 275: 100.00
+	Hs
		985945 PTN11_HUMAN (622-723): 5.34e-12: 71: 24.56		GOGA2_HUMAN (1-1002): 2.79e-77: 275: 100.00
+	Hs
		523231 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		MYH4_HUMAN (421-973): 1.1e-20: 100: 12.27
+	Hs
		412287 FYN_HUMAN (556-721): 1.61e-31: 131: 20.69		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		434048 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		DAPLE_HUMAN (329-961): 1.5e-14: 80.7: 13.08
+	Hs
		411743 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		GRDN_HUMAN (407-1001): 1.78e-12: 74: 10.63
+	Hs
		412058 FYN_HUMAN (556-721): 1.61e-31: 131: 20.69		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		433795 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		GRDN_HUMAN (407-1001): 1.78e-12: 74: 10.63
+	Hs
		111443 J3QRU1_HUMAN (556-728): 1.03e-30: 129: 19.34		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		433272 YES_HUMAN (556-728): 9.82e-31: 129: 19.34		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		433620 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		724720 BLK_HUMAN (556-724): 7.19e-29: 123: 22.16		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		725134 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		MYH10_HUMAN (449-991): 1.35e-23: 110: 9.74
+	Dm
		113911 M9PAY7_DROME (320-471): 8.07e-14: 72.5: 24.84		MYSN_DROME (453-976): 4.74e-18: 92.1: 10.09
+	Hs
		924736 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		724756 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		728465 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		MYH11_HUMAN (664-1000): 6.52e-11: 69: 14.45