HitPredict

Interactor 1: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Interactor 2: ZN408 (Q9H9D4)
Zinc finger protein 408 (PR domain zinc finger protein 17)
Gene: ZNF408

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4008 Hs			1 720
+	Hs
		1437017 NOTC3_HUMAN (355-1145): 4.51e-55: 217: 12.17		ZN408_HUMAN (11-720): 0: 602: 100.00
+	Hs
		1047744 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN408_HUMAN (11-720): 0: 602: 100.00
+	Hs
		1047774 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN107_HUMAN (262-719): 1.76e-171: 512: 23.92
+	Hs
		1387707 VWCE_HUMAN (355-1051): 5.53e-12: 74.5: 14.40		ZN408_HUMAN (11-720): 0: 602: 100.00
+	Hs
		1047607 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZSCA2_HUMAN (400-718): 1.87e-149: 450: 28.00
+	Hs
		1047770 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN629_HUMAN (548-717): 1.35e-70: 249: 22.86
+	Hs
		601934 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZNF7_HUMAN (470-686): 2.61e-68: 239: 27.85
+	Hs
		1047661 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN431_HUMAN (517-662): 7.7e-46: 174: 24.00
+	Hs
		271002 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN623_HUMAN (287-460): 1.99e-43: 166: 25.86
+	Hs
		1047638 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN709_HUMAN (425-648): 3.73e-38: 152: 35.78
+	Hs
		1044409 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZNF92_HUMAN (287-456): 1.13e-36: 147: 25.29
+	Hs
		1047667 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN480_HUMAN (560-664): 8.57e-28: 120: 20.95
+	Hs
		1047543 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN235_HUMAN (170-346): 1.44e-24: 111: 8.48
+	Hs
		71007 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN724_HUMAN (156-349): 8.59e-24: 108: 7.73
+	Hs
		913717 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN136_HUMAN (353-468): 3.19e-22: 103: 38.79
+	Hs
		276737 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN253_HUMAN (491-650): 2.52e-21: 100: 32.92
+	Hs
		1047764 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN624_HUMAN (143-263): 1.93e-19: 95.4: 7.32
+	Hs
		599953 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN708_HUMAN (267-356): 1.11e-16: 85.8: 13.33
+	Hs
		510069 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		ZN888_HUMAN (142-236): 7.47e-10: 64.2: 7.22
+	Hs
		913731 NELL2_HUMAN (23-499): 1.93e-09: 66.2: 22.65		ZN136_HUMAN (353-468): 3.19e-22: 103: 38.79