HitPredict

Interactor 1: LRCH3 (Q96II8)
DISP complex protein LRCH3 (Leucine-rich repeat and calponin homology domain-containing protein 3)
Gene: LRCH3

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	29467281, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 1294
+	Hs
		264522 LRCH4_HUMAN (46-399): 4.3e-57: 209: 54.17		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1357264 LRCH1_HUMAN (2-226): 1.49e-28: 124: 22.81		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1138592 LRCH2_HUMAN (12-153): 3.64e-14: 78.6: 16.44		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1023243 FLII_HUMAN (1-395): 2.24e-54: 205: 20.70		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		724803 FLII_HUMAN (1-395): 2.24e-54: 205: 20.70		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		522632 LRC39_HUMAN (47-170): 7.69e-20: 93.7: 25.78		MYH7_HUMAN (766-1261): 3.15e-15: 83.6: 11.01
+	Hs
		528387 LRC39_HUMAN (47-170): 7.69e-20: 93.7: 25.78		MYH6_HUMAN (760-1113): 5.54e-10: 66.2: 18.89
+	Hs
		1288117 LRC39_HUMAN (47-170): 7.69e-20: 93.7: 25.78		MYO5B_HUMAN (1016-1294): 4.73e-09: 63.4: 12.41