HitPredict

Interactor 1: ITCH (Q96J02)
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
Gene: ITCH

Interactor 2: CUED1 (Q9NWM3)
CUE domain-containing protein 1
Gene: CUEDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 903 Hs			1 386
+	Hs
		1327924 WWP1_HUMAN (1-903): 0: 832: 57.54		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1299649 NED4L_HUMAN (5-900): 0: 762: 32.14		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		808293 NEDD4_HUMAN (90-900): 0: 673: 34.16		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1336093 SMUF1_HUMAN (1-535): 1.85e-47: 183: 14.71		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1334875 SMUF2_HUMAN (1-358): 2.56e-46: 180: 16.94		CUED1_HUMAN (1-386): 0: 606: 100.00
+	Hs
		1347233 HECW2_HUMAN (1-512): 1.38e-13: 77.2: 11.34		CUED1_HUMAN (1-386): 0: 606: 100.00