HitPredict

Interactor 1: TMX3 (Q96JJ7)
Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3)
Gene: TMX3

Interactor 2: DJC25 (Q9H1X3)
DnaJ homolog subfamily C member 25
Gene: DNAJC25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 360
+	Hs
		531980 PDIA4_HUMAN (10-130): 1.56e-21: 99.5: 25.20		DJC25_HUMAN (1-360): 4.96e-100: 301: 100.00
+	Hs
		423356 PDIA1_HUMAN (23-128): 2.75e-21: 98.3: 29.73		DJC25_HUMAN (1-360): 4.96e-100: 301: 100.00
+	Hs
		1067840 PDIA6_HUMAN (2-365): 1.77e-62: 210: 17.06		DJB12_HUMAN (32-196): 4.9e-36: 136: 24.24
+	Hs
		1067846 PDIA6_HUMAN (2-365): 1.77e-62: 210: 17.06		DJB11_HUMAN (28-136): 5.33e-36: 135: 36.70
+	Hs
		1067845 PDIA6_HUMAN (2-365): 1.77e-62: 210: 17.06		DNJB9_HUMAN (39-124): 1.01e-26: 107: 33.72
+	Dm
		1359554 PDIA6_DROME (1-365): 1.15e-62: 211: 17.42		Q9VHA8_DROME (48-136): 1.86e-10: 63.9: 35.64
+	Hs
		532015 PDIA4_HUMAN (10-130): 1.56e-21: 99.5: 25.20		SEC63_HUMAN (18-341): 1.43e-40: 153: 17.71
+	Hs
		423386 PDIA1_HUMAN (23-128): 2.75e-21: 98.3: 29.73		SEC63_HUMAN (18-341): 1.43e-40: 153: 17.71
+	Hs
		671939 PDIA3_HUMAN (14-136): 6.09e-23: 103: 30.47		DJB12_HUMAN (32-196): 4.9e-36: 136: 24.24
+	Hs
		671948 PDIA3_HUMAN (14-136): 6.09e-23: 103: 30.47		DJB11_HUMAN (28-136): 5.33e-36: 135: 36.70
+	Hs
		636249 PDIA3_HUMAN (14-136): 6.09e-23: 103: 30.47		DNJB1_HUMAN (48-250): 2.68e-35: 133: 18.45
+	Hs
		532000 PDIA4_HUMAN (10-130): 1.56e-21: 99.5: 25.20		DJB12_HUMAN (32-196): 4.9e-36: 136: 24.24
+	Hs
		532011 PDIA4_HUMAN (10-130): 1.56e-21: 99.5: 25.20		DJB11_HUMAN (28-136): 5.33e-36: 135: 36.70
+	Hs
		423372 PDIA1_HUMAN (23-128): 2.75e-21: 98.3: 29.73		DJB12_HUMAN (32-196): 4.9e-36: 136: 24.24
+	Hs
		423380 PDIA1_HUMAN (23-128): 2.75e-21: 98.3: 29.73		DJB11_HUMAN (28-136): 5.33e-36: 135: 36.70
+	Hs
		671947 PDIA3_HUMAN (14-136): 6.09e-23: 103: 30.47		DNJB9_HUMAN (39-124): 1.01e-26: 107: 33.72
+	Hs
		532010 PDIA4_HUMAN (10-130): 1.56e-21: 99.5: 25.20		DNJB9_HUMAN (39-124): 1.01e-26: 107: 33.72
+	Hs
		423379 PDIA1_HUMAN (23-128): 2.75e-21: 98.3: 29.73		DNJB9_HUMAN (39-124): 1.01e-26: 107: 33.72
+	Hs
		671964 PDIA3_HUMAN (14-136): 6.09e-23: 103: 30.47		DJC16_HUMAN (49-128): 4.13e-11: 66.2: 43.75
+	Hs
		532027 PDIA4_HUMAN (10-130): 1.56e-21: 99.5: 25.20		DJC16_HUMAN (49-128): 4.13e-11: 66.2: 43.75