Protein: TF2L1
Transcription factor CP2-like protein 1 (CP2-related transcriptional repressor 1) (CRTR-1)

Gene: TF2L1, Tfcp2l1
Organism: Mus musculus
Interactions: 151
UniProt ID: Q3UNW5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000902 - cell morphogenesis
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1190709

TFCP2
Alpha-globin transcription factor CP2

2

14

High-throughput

0.817

High

1190649

UBIP1
Upstream-binding protein 1

1

14

High-throughput

0.691

High

1190670

GRHL2
Grainyhead-like protein 2 homolog

1

14

High-throughput

0.691

High

1190624

ERR2
Steroid hormone receptor ERR2

2

11

High-throughput

0.621

High

60007

ARI1A
AT-rich interactive domain-containing protein 1A

1

6

High-throughput

0.536

High

73070

ZN462
Zinc finger protein 462

1

2

High-throughput

0.536

High

98337

E9QLK7
Transformation/transcription domain-associated protein

1

3

High-throughput

0.536

High

148687

HDAC1
Histone deacetylase 1

1

3

High-throughput

0.536

High

266699

ZN143
Zinc finger protein 143

1

2

High-throughput

0.536

High

312021

WIZ
Protein Wiz

1

1

High-throughput

0.536

High

629258

PO5F1
POU domain, class 5, transcription factor 1

1

8

High-throughput

0.536

High

659099

XRCC6
X-ray repair cross-complementing protein 6

1

4

High-throughput

0.536

High

694276

XRCC5
X-ray repair cross-complementing protein 5

1

4

High-throughput

0.536

High

928603

MSH6
DNA mismatch repair protein Msh6

1

2

High-throughput

0.536

High

947429

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

2

High-throughput

0.536

High

949040

RUVB1
RuvB-like 1

1

4

High-throughput

0.536

High

965386

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.536

High

1000001

HDAC2
Histone deacetylase 2

1

4

High-throughput

0.536

High

1021139

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

High-throughput

0.536

High

1021774

SMRC1
SWI/SNF complex subunit SMARCC1

1

2

High-throughput

0.536

High

1189428

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

3

High-throughput

0.536

High

1189618

YETS2
YEATS domain-containing protein 2

1

6

High-throughput

0.536

High

1190612

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

High-throughput

0.536

High

1190615

SIN3A
Paired amphipathic helix protein Sin3a

1

1

High-throughput

0.536

High

1190617

HELLS
Lymphocyte-specific helicase

1

4

High-throughput

0.536

High

1190619

RBBP7
Histone-binding protein RBBP7

1

3

High-throughput

0.536

High

1190621

REQU
Zinc finger protein ubi-d4

1

6

High-throughput

0.536

High

1190622

HCFC1
Host cell factor 1

1

1

High-throughput

0.536

High

1190627

PHC1
Polyhomeotic-like protein 1

1

6

High-throughput

0.536

High

1190634

SMRC2
SWI/SNF complex subunit SMARCC2

1

3

High-throughput

0.536

High

1190636

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

2

High-throughput

0.536

High

1190637

RIF1
Telomere-associated protein RIF1

1

2

High-throughput

0.536

High

1190639

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.536

High

1190644

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

3

High-throughput

0.536

High

1190654

SALL4
Sal-like protein 4

1

6

High-throughput

0.536

High

1190660

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.536

High

1190663

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.536

High

1190667

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

5

High-throughput

0.536

High

1190668

DPOLB
DNA polymerase beta

1

1

High-throughput

0.536

High

1190669

MTA1
Metastasis-associated protein MTA1

1

5

High-throughput

0.536

High

1190675

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.536

High

1190678

SATB2
DNA-binding protein SATB2

1

1

High-throughput

0.536

High

1190681

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

3

High-throughput

0.536

High

1190684

MTA3
Metastasis-associated protein MTA3

1

5

High-throughput

0.536

High

1190686

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

4

High-throughput

0.536

High

1190690

PCGF6
Polycomb group RING finger protein 6

1

7

High-throughput

0.536

High

1190691

UBQL4
Ubiquilin-4

1

3

High-throughput

0.536

High

1190692

TRI33
E3 ubiquitin-protein ligase TRIM33

1

1

High-throughput

0.536

High

1190696

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.536

High

1190712

MTA2
Metastasis-associated protein MTA2

1

5

High-throughput

0.536

High

1190713

RUVB2
RuvB-like 2

1

4

High-throughput

0.536

High

1190716

MBD3
Methyl-CpG-binding domain protein 3

1

1

High-throughput

0.536

High

1190717

MBD2
Methyl-CpG-binding domain protein 2

1

1

High-throughput

0.536

High

59865

MGAP
MAX gene-associated protein

1

0

High-throughput

0.513

High

878199

MYBB
Myb-related protein B

1

0

High-throughput

0.513

High

1190641

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.513

High

1190676

ING3
Inhibitor of growth protein 3

1

0

High-throughput

0.513

High

1190682

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.513

High

1190707

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.513

High

1190710

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

1190714

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.513

High

236730

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

1

High-throughput

0.489

High

1190616

XRCC1
DNA repair protein XRCC1

1

1

High-throughput

0.489

High

1190623

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

1

High-throughput

0.489

High

1190650

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

6

High-throughput

0.489

High

1190664

EP400
E1A-binding protein p400

1

4

High-throughput

0.489

High

1190671

BRD8
Bromodomain-containing protein 8

1

5

High-throughput

0.489

High

1190687

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

1

High-throughput

0.489

High

1190697

YETS4
YEATS domain-containing protein 4

1

1

High-throughput

0.489

High

98166

E9Q6A7
Bromodomain PHD finger transcription factor

1

6

High-throughput

0.479

High

749846

KIF5A
Kinesin heavy chain isoform 5A

1

1

High-throughput

0.479

High

846145

CDX2
Homeobox protein CDX-2

1

3

High-throughput

0.479

High

846710

MSH2
DNA mismatch repair protein Msh2

1

2

High-throughput

0.479

High

1190631

Q6P5E3
Sal-like protein 1

1

6

High-throughput

0.479

High

1190638

Q6ZQ47
Activity-dependent neuroprotector homeobox protein

1

1

High-throughput

0.479

High

1190646

Q80X22
Cabin1 protein

1

1

High-throughput

0.479

High

1190655

POGZ
Pogo transposable element with ZNF domain

1

2

High-throughput

0.479

High

1190658

RBM4
RNA-binding protein 4

1

3

High-throughput

0.479

High

1190665

P66A
Transcriptional repressor p66 alpha

1

4

High-throughput

0.479

High

1190677

P66B
Transcriptional repressor p66-beta

1

4

High-throughput

0.479

High

1190718

ACL6A
Actin-like protein 6A

1

4

High-throughput

0.479

High

51270

A1L3S7
GATA zinc finger domain containing 2B

1

4

High-throughput

0.445

High

59036

A2A654
Bromodomain PHD finger transcription factor

1

7

High-throughput

0.445

High

59237

MED14
Mediator of RNA polymerase II transcription subunit 14

1

4

High-throughput

0.445

High

59311

MED12
Mediator of RNA polymerase II transcription subunit 12

1

4

High-throughput

0.445

High

98367

E9QMN5
GATA zinc finger domain containing 2A

1

4

High-throughput

0.445

High

108250

G3X8Q1
Calcineurin-binding protein cabin-1

1

1

High-throughput

0.445

High

147637

ERR1
Steroid hormone receptor ERR1

1

11

High-throughput

0.445

High

1081842

Q0VGT3
Pogo transposable element with ZNF domain

1

2

High-throughput

0.445

High

1190613

Q5RKY4
Activity-dependent neuroprotector homeobox protein

1

1

High-throughput

0.445

High

1190614

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.445

High

1190618

RBBP4
Histone-binding protein RBBP4

1

3

High-throughput

0.445

High

1190620

NR0B1
Nuclear receptor subfamily 0 group B member 1

1

12

High-throughput

0.445

High

1190625

TAF6
Transcription initiation factor TFIID subunit 6

1

1

High-throughput

0.445

High

1190633

FKB15
FK506-binding protein 15

1

3

High-throughput

0.445

High

1190645

Q80VS1
Esrrb protein

1

11

High-throughput

0.445

High

1190651

KMT2C
Histone-lysine N-methyltransferase 2C

1

6

High-throughput

0.445

High

1190652

PB1
Protein polybromo-1

1

4

High-throughput

0.445

High

1190653

RBBP5
Retinoblastoma-binding protein 5

1

3

High-throughput

0.445

High

1190657

RBM14
RNA-binding protein 14

1

3

High-throughput

0.445

High

1190661

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

7

High-throughput

0.445

High

1190672

CDK8
Cyclin-dependent kinase 8

1

2

High-throughput

0.445

High

1190680

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

3

High-throughput

0.445

High

1190685

MED1
Mediator of RNA polymerase II transcription subunit 1

1

2

High-throughput

0.445

High

1190708

SALL1
Sal-like protein 1

1

6

High-throughput

0.445

High

1190711

PNKP
Bifunctional polynucleotide phosphatase/kinase

1

2

High-throughput

0.445

High

1190715

KLF5
Krueppel-like factor 5

1

5

High-throughput

0.445

High

97869

E9Q2I4
Mitotic deacetylase associated SANT domain protein

1

5

High-throughput

0.437

High

109315

G5E8N7
Bifunctional polynucleotide phosphatase/kinase

1

2

High-throughput

0.437

High

1190648

Q80ZH7
DNA ligase

1

2

High-throughput

0.437

High

706371

TBP
TATA-box-binding protein

1

0

High-throughput

0.426

High

1021838

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.426

High

1190628

JHD2C
Probable JmjC domain-containing histone demethylation protein 2C

1

0

High-throughput

0.426

High

1190640

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.426

High

1190647

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.426

High

1190656

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

1190659

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.426

High

1190662

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.426

High

1190666

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.426

High

1190673

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.426

High

1190674

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.426

High

1190679

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.426

High

1190683

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.426

High

1190688

Q99JW7
Cdc2a protein

1

0

High-throughput

0.426

High

1190689

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.426

High

1190693

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.426

High

1190695

MED30
Mediator of RNA polymerase II transcription subunit 30

1

0

High-throughput

0.426

High

1190699

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.426

High

1190700

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.426

High

1190702

KAT8
Histone acetyltransferase KAT8

1

0

High-throughput

0.426

High

1190705

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.426

High

1190706

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

1021284

DNLI3
DNA ligase 3

1

2

High-throughput

0.407

High

1190629

Q6GQS5
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.407

High

1190635

KMT2D
Histone-lysine N-methyltransferase 2D

1

9

High-throughput

0.407

High

1190642

Q7TQE1
Mediator of RNA polymerase II transcription subunit 15

1

5

High-throughput

0.407

High

1190643

Q80V79
DNA mismatch repair protein

1

2

High-throughput

0.407

High

1190701

RAB32
Ras-related protein Rab-32

1

1

High-throughput

0.407

High

59074

ZMYM4
Zinc finger MYM-type protein 4

1

0

High-throughput

0.279

Low

60463

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.279

Low

1190626

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.279

Low

1190630

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.279

Low

1190694

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.279

Low

1190698

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

0

High-throughput

0.279

Low

1190703

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.279

Low

1190611

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.249

Low

107949

G3UW74
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.232

Low

148413

O08847
DNA-directed RNA polymerase subunit

1

0

High-throughput

0.232

Low

1053212

Q05BA5
Nuclear receptor coactivator

1

0

High-throughput

0.232

Low

1190632

Q6P6A2
Cyclin-C

1

0

High-throughput

0.232

Low

1190704

Q9DAY7
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025