Protein: FANCL
E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL)

Gene: FANCL
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q9NW38

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1342651

UBE2T
Ubiquitin-conjugating enzyme E2 T

15

0

Small-scale

0.935

High

1284890

UBE2W
Ubiquitin-conjugating enzyme E2 W

3

2

Small-scale

0.840

High

1347066

FANCL
E3 ubiquitin-protein ligase FANCL

2

1

Small-scale

0.768

High

1315882

FACD2
Fanconi anemia group D2 protein

13

2

Small-scale

0.760

High

1346600

FANCI
Fanconi anemia group I protein

8

3

Small-scale

0.745

High

176647

FANCA
Fanconi anemia group A protein

15

0

Small-scale

0.727

High

1223015

FANCM
Fanconi anemia group M protein

10

0

Small-scale

0.718

High

174441

FANCG
Fanconi anemia group G protein

5

1

Small-scale

0.702

High

1012635

FP100
Fanconi anemia core complex-associated protein 100

4

0

Small-scale

0.663

High

1347067

MIC19
MICOS complex subunit MIC19

3

0

High-throughput

0.646

High

1239629

FANCB
Fanconi anemia group B protein

3

0

Small-scale

0.630

High

1342903

FANCF
Fanconi anemia group F protein

3

0

Small-scale

0.619

High

960714

FANCC
Fanconi anemia group C protein

3

0

Small-scale

0.613

High

446880

HXD4
Homeobox protein Hox-D4

2

1

High-throughput

0.606

High

517494

PCNA
Proliferating cell nuclear antigen

2

0

Small-scale

0.603

High

554526

GATA1
Erythroid transcription factor

2

0

High-throughput

0.580

High

970607

ID2
DNA-binding protein inhibitor ID-2

2

0

High-throughput

0.580

High

1109421

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.580

High

1119880

KR132
Keratin-associated protein 13-2

2

0

High-throughput

0.580

High

1149957

NB5R2
NADH-cytochrome b5 reductase 2

2

0

High-throughput

0.580

High

1161297

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.580

High

1216025

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.580

High

1293005

SNF8
Vacuolar-sorting protein SNF8

2

0

High-throughput

0.580

High

1311241

HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3

2

0

High-throughput

0.580

High

1314681

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.580

High

1326695

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

2

0

High-throughput

0.580

High

1347069

ZN581
Zinc finger protein 581

2

0

High-throughput

0.580

High

1347077

RNF11
RING finger protein 11

2

0

High-throughput

0.580

High

67746

CENPX
Centromere protein X

2

0

Small-scale

0.559

High

1157502

FAP20
Fanconi anemia core complex-associated protein 20

2

0

Small-scale

0.559

High

1016880

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.549

High

1216455

RBM45
RNA-binding protein 45

1

0

High-throughput

0.549

High

1244082

DOCK8
Dedicator of cytokinesis protein 8

1

0

High-throughput

0.549

High

1310179

LZTS2
Leucine zipper putative tumor suppressor 2

1

0

High-throughput

0.549

High

1344399

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.549

High

1347071

RIM3A
RIMS-binding protein 3A

1

0

High-throughput

0.549

High

1347073

IKZF3
Zinc finger protein Aiolos

1

0

High-throughput

0.549

High

1347076

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.549

High

1054247

HES1
Transcription factor HES-1

1

0

Small-scale

0.529

High

1263412

ATRIP
ATR-interacting protein

1

0

Small-scale

0.529

High

181470

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.513

High

583821

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

958532

CYC
Cytochrome c

1

0

High-throughput

0.513

High

1073946

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.513

High

1312267

FAP24
Fanconi anemia core complex-associated protein 24

1

0

Small-scale

0.513

High

200793

ARHG9
Rho guanine nucleotide exchange factor 9

1

0

High-throughput

0.493

High

832047

PSB3
Proteasome subunit beta type-3

1

0

High-throughput

0.493

High

1108740

ANR55
Ankyrin repeat domain-containing protein 55

1

0

High-throughput

0.493

High

1157047

ZN774
Zinc finger protein 774

1

0

High-throughput

0.493

High

1347068

ZN224
Zinc finger protein 224

1

0

High-throughput

0.493

High

1347070

ZMAT5
Zinc finger matrin-type protein 5

1

0

High-throughput

0.493

High

1347075

SNX7
Sorting nexin-7

1

1

High-throughput

0.489

High

1347074

CAPS1
Calcium-dependent secretion activator 1

1

1

High-throughput

0.481

High

1347078

SNX11
Sorting nexin-11

1

1

High-throughput

0.470

High

58006

A2RRN7
CADPS protein

1

1

High-throughput

0.470

High

898081

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.460

High

1032644

CTBP1
C-terminal-binding protein 1

1

0

Small-scale

0.460

High

749896

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

803775

BAG6
Large proline-rich protein BAG6

1

0

Small-scale

0.458

High

1231903

CENPS
Centromere protein S

1

0

Small-scale

0.458

High

1313794

KIFC3
Kinesin-like protein KIFC3

3

0

High-throughput

0.352

High

445730

IL6RA
Interleukin-6 receptor subunit alpha

2

0

High-throughput

0.328

High

1204526

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

0

High-throughput

0.328

High

1347072

CLC2D
C-type lectin domain family 2 member D

2

0

High-throughput

0.328

High

63469

MET15
12S rRNA N4-methylcytidine

2

0

High-throughput

0.316

High

326938

DDAH2
Putative hydrolase DDAH2

2

0

High-throughput

0.316

High

1124850

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

1133342

GT253
Inactive glycosyltransferase 25 family member 3

2

0

High-throughput

0.316

High

1156838

UFSP1
Inactive Ufm1-specific protease 1

2

0

High-throughput

0.316

High

1309465

ANKMT
Adenine nucleotide translocase lysine N-methyltransferase

2

0

High-throughput

0.316

High

660728

GRN
Progranulin

1

0

High-throughput

0.299

High

1222766

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.299

High

1245473

GP150
Probable G-protein coupled receptor 150

1

0

High-throughput

0.279

Low

67373

CRTP1
Cysteine-rich tail protein 1

1

0

High-throughput

0.268

Low

1140030

TTC23
Tetratricopeptide repeat protein 23

1

0

High-throughput

0.268

Low

1221274

Q8IXS7
SRGAP3 protein

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024