Interactor 1: KLOTB (Q86Z14)
Beta-klotho (BKL) (BetaKlotho) (Klotho beta-like protein)
Gene: KLB
Interactor 2: FGF21 (Q9NSA1)
Fibroblast growth factor 21 (FGF-21)
Gene: FGF21
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19059246 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FGF~Glyco_hydro_1 |
| Common GO terms | GO:0005104 - fibroblast growth factor receptor binding GO:0008284 - positive regulation of cell population proliferation GO:0090080 - positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
