HitPredict - High confidence protein-protein interactions

Protein: KLOT
Klotho (EC 3.2.1.31) [Cleaved into: Klotho peptide]

Gene: KLOT, KL
Organism: Homo sapiens
Interactions: 5
UniProt ID: Q9UEF7

Gene Ontology (top 5):
GO:0003085 - negative regulation of systemic arterial blood pressure
GO:0004566 - beta-glucuronidase activity
GO:0005104 - fibroblast growth factor receptor binding
GO:0005179 - hormone activity
GO:0005499 - vitamin D binding

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1429063	FGF23 Fibroblast growth factor 23	1	1	Small-scale	0.618	High
1028433	MDM2 E3 ubiquitin-protein ligase Mdm2	1	0	Small-scale	0.458	High
1458979	SHAN1 SH3 and multiple ankyrin repeat domains protein 1	1	0	Small-scale	0.458	High
345127	RIGI Antiviral innate immune response receptor RIG-I	1	1	Small-scale	0.437	High
1361091	MYO3B Myosin-IIIb	1	0	High-throughput	0.279	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025