Interactor 1: FGF23 (Q9GZV9)
Fibroblast growth factor 23 (FGF-23) (Phosphatonin) (Tumor-derived hypophosphatemia-inducing factor) [Cleaved into: Fibroblast growth factor 23 N-terminal peptide; Fibroblast growth factor 23 C-terminal peptide]
Gene: FGF23
Interactor 2: KLOT (Q9UEF7)
Klotho (EC 3.2.1.31) [Cleaved into: Klotho peptide]
Gene: KL
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27879395 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FGF~Glyco_hydro_1 |
| Common GO terms | GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0008543 - fibroblast growth factor receptor signaling pathway GO:0055074 - calcium ion homeostasis GO:0090080 - positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
 |
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
