HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: NFIB (O00712)
Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein)
Gene: NFIB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 560 Hs			1 420
+	Hs
		129731 CBX4_HUMAN (1-560): 7.61e-163: 477: 100.00		NFIX_HUMAN (2-414): 0: 614: 61.70
+	Hs
		129643 CBX4_HUMAN (1-560): 7.61e-163: 477: 100.00		NFIC_HUMAN (1-412): 0: 603: 64.86
+	Hs
		129725 CBX4_HUMAN (1-560): 7.61e-163: 477: 100.00		NFIA_HUMAN (2-414): 0: 573: 63.12
+	Hs
		142997 CBX2_HUMAN (2-559): 1.2e-82: 269: 23.54		NFIB_HUMAN (1-420): 0: 702: 100.00
+	Hs
		1132190 CBX2_HUMAN (2-559): 1.2e-82: 269: 23.54		NFIX_HUMAN (2-414): 0: 614: 61.70
+	Hs
		473991 CBX2_HUMAN (2-559): 1.2e-82: 269: 23.54		NFIC_HUMAN (1-412): 0: 603: 64.86
+	Hs
		142887 CBX5_HUMAN (11-171): 7.07e-41: 148: 19.88		NFIB_HUMAN (1-420): 0: 702: 100.00
+	Hs
		142937 CBX1_HUMAN (17-163): 1.9e-39: 144: 21.05		NFIB_HUMAN (1-420): 0: 702: 100.00
+	Hs
		1087742 CBX2_HUMAN (2-559): 1.2e-82: 269: 23.54		NFIA_HUMAN (2-414): 0: 573: 63.12
+	Hs
		1133745 CDYL_HUMAN (2-288): 4.49e-50: 183: 16.35		NFIX_HUMAN (2-414): 0: 614: 61.70
+	Hs
		474383 CDYL_HUMAN (2-288): 4.49e-50: 183: 16.35		NFIC_HUMAN (1-412): 0: 603: 64.86
+	Hs
		853261 CBX5_HUMAN (11-171): 7.07e-41: 148: 19.88		NFIX_HUMAN (2-414): 0: 614: 61.70
+	Hs
		1014100 CBX1_HUMAN (17-163): 1.9e-39: 144: 21.05		NFIX_HUMAN (2-414): 0: 614: 61.70
+	Hs
		1088109 CDYL_HUMAN (2-288): 4.49e-50: 183: 16.35		NFIA_HUMAN (2-414): 0: 573: 63.12
+	Hs
		473848 CBX5_HUMAN (11-171): 7.07e-41: 148: 19.88		NFIC_HUMAN (1-412): 0: 603: 64.86
+	Hs
		473914 CBX1_HUMAN (17-163): 1.9e-39: 144: 21.05		NFIC_HUMAN (1-412): 0: 603: 64.86
+	Hs
		853238 CBX5_HUMAN (11-171): 7.07e-41: 148: 19.88		NFIA_HUMAN (2-414): 0: 573: 63.12
+	Hs
		1014078 CBX1_HUMAN (17-163): 1.9e-39: 144: 21.05		NFIA_HUMAN (2-414): 0: 573: 63.12