HitPredict

Interactor 1: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Interactor 2: ACE2 (Q9BYF1)
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
Gene: ACE2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.50	0.639

Property	Details
Experiments	35022217, 36057605, 34835087, 33436498
Identification Methods	unspecified method, x-ray crystallography, affinity chromatography technology, pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 805
+	Hs
		1065084 SNX17_HUMAN (162-535): 9.12e-108: 331: 25.31		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1191869 GRASP_HUMAN (7-172): 1.34e-36: 142: 24.86		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1316849 SHAN1_HUMAN (43-169): 7.26e-32: 133: 30.71		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1316822 SHAN2_HUMAN (43-147): 7.14e-29: 124: 38.10		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1075451 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1316272 SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		153946 NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1132917 NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70		ACE2_HUMAN (12-805): 0: 1184: 100.00