Interactor 1: NALP4 (Q96MN2)
NACHT, LRR and PYD domains-containing protein 4 (Cancer/testis antigen 58) (CT58) (PAAD and NACHT-containing protein 2) (PAN2) (PYRIN and NACHT-containing protein 2) (PYRIN-containing APAF1-like protein 4) (PYPAF4) (Ribonuclease inhibitor 2)
Gene: NLRP4

Interactor 2: NLRC4 (Q9NPP4)
NLR family CARD domain-containing protein 4 (CARD, LRR, and NACHT-containing protein) (CED-4-like protein Clan) (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf)
Gene: NLRC4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15107016
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains NACHT~NACHT, NACHT~NLRC4_HD, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD~NOD2_WH
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006954 - inflammatory response
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 994
Hs

1 1024
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Last updated: 15 Jul 2024