Interactor 1: ARHGH (Q96PE2)
Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)
Gene: ARHGEF17

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31586073
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT~RhoGEF, RhoGEF~RhoGEF
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0051056 - regulation of small GTPase mediated signal transduction
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 2063
Hs

1 914
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Last updated: 15 Jul 2024