HitPredict

Interactor 1: ELL2 (O00472)
RNA polymerase II elongation factor ELL2
Gene: ELL2

Interactor 2: EAF1 (Q96JC9)
ELL-associated factor 1
Gene: EAF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.965

Property	Details
Experiments	26186194, 28514442, 11418481, 33961781, 21729782, 32296183, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	EAF~ELL
Common GO terms	GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0008023 - transcription elongation factor complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 640 Hs			1 268
+	Hs
		130168 ELL2_HUMAN (1-640): 0: 750: 100.00		EAF2_HUMAN (1-268): 2.26e-102: 300: 54.35
+	Hs
		876661 ELL_HUMAN (7-639): 0: 646: 45.92		EAF1_HUMAN (1-268): 3.16e-103: 303: 100.00
+	Hs
		876658 ELL_HUMAN (7-639): 0: 646: 45.92		EAF2_HUMAN (1-268): 2.26e-102: 300: 54.35
+	Hs
		1295112 ELL3_HUMAN (26-275): 2.78e-31: 128: 21.22		EAF1_HUMAN (1-268): 3.16e-103: 303: 100.00
+	Hs
		1286797 ELL3_HUMAN (26-275): 2.78e-31: 128: 21.22		EAF2_HUMAN (1-268): 2.26e-102: 300: 54.35