Interactor 1: NR5A2 (O00482)
Nuclear receptor subfamily 5 group A member 2 (Alpha-1-fetoprotein transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Hepatocytic transcription factor) (Liver receptor homolog 1) (LRH-1)
Gene: NR5A2

Interactor 2: NR0B2 (Q15466)
Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner)
Gene: NR0B2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 12198243, 27486225, 20375098, 20516075, 21566081, 11668176, 21262773, 14963109, 22504882
Identification Methods pull down, two hybrid, affinity chromatography technology, fluorescence polarization spectroscopy, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 541
Hs

1 257
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024