HitPredict

Interactor 1: SEC62 (Q99442)
Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1)
Gene: SEC62

Interactor 2: OSBL8 (Q9BZF1)
Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)
Gene: OSBPL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	32788342, 34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 889
+	Hs
		1303554 SEC62_HUMAN (1-399): 0: 548: 100.00		OSBL5_HUMAN (32-889): 0: 1012: 54.21
+	Hs
		1302526 SEC62_HUMAN (1-399): 0: 548: 100.00		OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32
+	Hs
		1303557 SEC62_HUMAN (1-399): 0: 548: 100.00		OSBL2_HUMAN (323-758): 4.85e-138: 421: 23.19
+	Hs
		1303544 SEC62_HUMAN (1-399): 0: 548: 100.00		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Sc
		601697 SEC62_YEAST (84-319): 6.93e-62: 202: 26.12		OSH7_YEAST (360-746): 3.93e-126: 389: 31.49