Protein: DTBP1
Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein)

Gene: DTBP1, DTNBP1
Organism: Homo sapiens
Interactions: 164
UniProt ID: Q96EV8

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0001956 - positive regulation of neurotransmitter secretion
GO:0002092 - positive regulation of receptor internalization
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

333386

SNAPN
SNARE-associated protein Snapin

10

1

Small-scale

0.757

High

1389809

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

9

1

Small-scale

0.755

High

1008488

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

6

1

Small-scale

0.730

High

1246494

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

6

1

Small-scale

0.730

High

1351260

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

7

0

Small-scale

0.716

High

1389801

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit 4

5

2

Small-scale

0.709

High

1325245

TXLNB
Beta-taxilin

4

1

High-throughput

0.707

High

1350688

CCHCR
Coiled-coil alpha-helical rod protein 1

4

1

High-throughput

0.705

High

1093398

TRI32
E3 ubiquitin-protein ligase TRIM32

4

4

Small-scale

0.702

High

1246468

BL1S3
Biogenesis of lysosome-related organelles complex 1 subunit 3

6

0

Small-scale

0.699

High

1389825

DTNA
Dystrobrevin alpha

4

6

Small-scale

0.698

High

158866

AP3D1
AP-3 complex subunit delta-1

4

2

High-throughput

0.691

High

1351356

BCAS4
Breast carcinoma-amplified sequence 4

4

1

High-throughput

0.691

High

1357192

BRK1
Protein BRICK1

4

0

High-throughput

0.675

High

1382565

EXOC4
Exocyst complex component 4

4

0

High-throughput

0.669

High

1389803

SYBU
Syntabulin

4

0

High-throughput

0.669

High

126165

AP3B1
AP-3 complex subunit beta-1

3

1

High-throughput

0.667

High

177038

CE290
Centrosomal protein of 290 kDa

3

1

High-throughput

0.667

High

1087024

KIF5A
Kinesin heavy chain isoform 5A

3

2

High-throughput

0.667

High

1103497

AP3B2
AP-3 complex subunit beta-2

3

1

High-throughput

0.667

High

1292735

TRI69
E3 ubiquitin-protein ligase TRIM69

3

1

High-throughput

0.667

High

1316693

ABI1
Abl interactor 1

3

2

High-throughput

0.667

High

1316856

ASPM
Abnormal spindle-like microcephaly-associated protein

3

4

High-throughput

0.667

High

1347239

EXOC6
Exocyst complex component 6

3

1

High-throughput

0.667

High

1364922

AP3S1
AP-3 complex subunit sigma-1

3

2

High-throughput

0.667

High

1389781

CYFP2
Cytoplasmic FMR1-interacting protein 2

3

1

High-throughput

0.667

High

1389797

KLC2
Kinesin light chain 2

3

2

High-throughput

0.667

High

1389799

MYO5C
Unconventional myosin-Vc

3

1

High-throughput

0.667

High

1389822

KIF3A
Kinesin-like protein KIF3A

3

2

High-throughput

0.667

High

1389824

MYO5A
Unconventional myosin-Va

3

1

High-throughput

0.667

High

1389815

EXOC7
Exocyst complex component 7

4

0

High-throughput

0.665

High

1217273

VPS53
Vacuolar protein sorting-associated protein 53 homolog

4

0

High-throughput

0.661

High

1389813

COG5
Conserved oligomeric Golgi complex subunit 5

4

0

High-throughput

0.661

High

1289118

TRI74
Tripartite motif-containing protein 74

3

2

High-throughput

0.657

High

749982

KINH
Kinesin-1 heavy chain

3

2

High-throughput

0.650

High

262419

DTNB
Dystrobrevin beta

2

6

Small-scale

0.641

High

137261

EXOC5
Exocyst complex component 5

3

0

High-throughput

0.638

High

252896

EXOC3
Exocyst complex component 3

3

0

High-throughput

0.638

High

281079

TACC1
Transforming acidic coiled-coil-containing protein 1

3

0

High-throughput

0.638

High

1211609

TEX35
Testis-expressed protein 35

3

0

High-throughput

0.638

High

1246145

TRAF7
E3 ubiquitin-protein ligase TRAF7

3

0

High-throughput

0.638

High

1288755

KTN1
Kinectin

3

0

High-throughput

0.638

High

1338095

NAV1
Neuron navigator 1

3

0

High-throughput

0.638

High

1385674

ENTR1
Endosome-associated-trafficking regulator 1

3

0

High-throughput

0.638

High

1389791

VAMP8
Vesicle-associated membrane protein 8

3

0

High-throughput

0.638

High

1389802

EXOC1
Exocyst complex component 1

3

0

High-throughput

0.638

High

1389805

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.638

High

1389806

VPS51
Vacuolar protein sorting-associated protein 51 homolog

3

0

High-throughput

0.638

High

1389812

STX8
Syntaxin-8

3

0

High-throughput

0.638

High

1389817

NCKP1
Nck-associated protein 1

3

0

High-throughput

0.638

High

1389819

AP3M1
AP-3 complex subunit mu-1

3

0

High-throughput

0.638

High

1389788

NECD
Necdin

3

0

Small-scale

0.628

High

1313676

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.616

High

718900

CCND3
G1/S-specific cyclin-D3

2

3

Small-scale

0.614

High

257157

CCD22
Coiled-coil domain-containing protein 22

2

1

High-throughput

0.611

High

1060561

KLC1
Kinesin light chain 1

2

2

High-throughput

0.611

High

1111474

IQGA2
Ras GTPase-activating-like protein IQGAP2

2

2

High-throughput

0.611

High

1272192

CYFP1
Cytoplasmic FMR1-interacting protein 1

2

1

High-throughput

0.611

High

1389818

EXC6B
Exocyst complex component 6B

3

1

High-throughput

0.609

High

1389807

TSKS
Testis-specific serine kinase substrate

2

0

High-throughput

0.602

High

1389808

GGA1
ADP-ribosylation factor-binding protein GGA1

2

0

High-throughput

0.602

High

1351573

MIPT3
TRAF3-interacting protein 1

2

0

High-throughput

0.588

High

181649

CETN3
Centrin-3

2

0

High-throughput

0.585

High

1097863

STX5
Syntaxin-5

2

0

High-throughput

0.585

High

1104861

SNTB2
Beta-2-syntrophin

2

0

High-throughput

0.585

High

1389785

SPAG5
Sperm-associated antigen 5

2

0

High-throughput

0.585

High

1389790

BBLN
Bublin coiled-coil protein

2

0

High-throughput

0.585

High

217178

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

341832

K2C75
Keratin, type II cytoskeletal 75

2

0

High-throughput

0.580

High

1279961

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.580

High

1294479

VRK2
Serine/threonine-protein kinase VRK2

1

4

Small-scale

0.578

High

572124

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.573

High

1389792

KIFC3
Kinesin-like protein KIFC3

1

1

High-throughput

0.573

High

664790

CCND1
G1/S-specific cyclin-D1

1

3

Small-scale

0.561

High

1178069

RN151
RING finger protein 151

1

4

Small-scale

0.561

High

51286

ELOV7
Very long chain fatty acid elongase 7

1

0

High-throughput

0.549

High

51369

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

1

0

High-throughput

0.549

High

140399

SDCB1
Syntenin-1

1

0

High-throughput

0.549

High

1193098

DRC12
Dynein regulatory complex protein 12

1

0

High-throughput

0.549

High

1276091

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.549

High

1314904

CC146
Coiled-coil domain-containing protein 146

1

0

High-throughput

0.549

High

1386259

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.549

High

1389800

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

1

0

High-throughput

0.549

High

1389804

ABI3
ABI gene family member 3

1

2

High-throughput

0.541

High

244864

TRAK2
Trafficking kinesin-binding protein 2

1

1

High-throughput

0.536

High

1242688

KLC3
Kinesin light chain 3

1

2

High-throughput

0.536

High

1277605

K1C27
Keratin, type I cytoskeletal 27

1

1

High-throughput

0.536

High

1330511

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

1

2

High-throughput

0.536

High

920592

ARFP2
Arfaptin-2

1

0

High-throughput

0.518

High

1389793

DGC6L
Protein DGCR6L

1

0

High-throughput

0.518

High

867814

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.513

High

994335

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.513

High

1098663

SBP1
Methanethiol oxidase

1

0

High-throughput

0.513

High

1236033

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.513

High

1286456

DSG4
Desmoglein-4

1

0

High-throughput

0.513

High

1353647

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.513

High

1389787

OSBL9
Oxysterol-binding protein-related protein 9

1

0

High-throughput

0.513

High

1389816

ANGP4
Angiopoietin-4

1

0

High-throughput

0.513

High

1092851

AKAP6
A-kinase anchor protein 6

1

5

High-throughput

0.508

High

1389814

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

4

High-throughput

0.508

High

705722

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

0

High-throughput

0.493

High

134118

IPO5
Importin-5

1

0

High-throughput

0.486

High

629154

CCNA2
Cyclin-A2

1

0

High-throughput

0.486

High

960522

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.486

High

976481

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.486

High

1293847

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

0

High-throughput

0.486

High

1339430

NBEA
Neurobeachin

1

0

High-throughput

0.486

High

1371350

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

High-throughput

0.486

High

1389798

RBNS5
Rabenosyn-5

1

0

High-throughput

0.486

High

1389810

ZN490
Zinc finger protein 490

1

0

High-throughput

0.486

High

238824

KALRN
Kalirin

1

2

High-throughput

0.481

High

1040356

DYST
Dystonin

1

4

High-throughput

0.481

High

1338565

SYNE1
Nesprin-1

1

5

High-throughput

0.481

High

1389794

NUF2
Kinetochore protein Nuf2

1

2

High-throughput

0.481

High

1389795

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

6

High-throughput

0.481

High

1389796

TRIM2
Tripartite motif-containing protein 2

1

5

High-throughput

0.481

High

332430

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

0

High-throughput

0.480

High

180896

TIF1A
Transcription intermediary factor 1-alpha

1

3

Small-scale

0.479

High

340206

PCNT
Pericentrin

1

1

High-throughput

0.479

High

594076

NCK1
SH2/SH3 adapter protein NCK1

1

1

High-throughput

0.479

High

699829

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

High-throughput

0.479

High

718834

CCND2
G1/S-specific cyclin-D2

1

3

Small-scale

0.479

High

948106

AP3S2
AP-3 complex subunit sigma-2

1

1

High-throughput

0.479

High

1350170

ALMS1
Centrosome-associated protein ALMS1

1

2

High-throughput

0.479

High

1389786

CK5P2
CDK5 regulatory subunit-associated protein 2

1

2

High-throughput

0.479

High

212778

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

0

High-throughput

0.460

High

1123753

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.460

High

173210

XPO1
Exportin-1

1

0

High-throughput

0.458

High

242564

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

619092

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.458

High

675105

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

904358

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.458

High

1233411

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1253921

FA83H
Protein FAM83H

1

0

High-throughput

0.458

High

1389823

DCAF1
DDB1- and CUL4-associated factor 1

1

0

High-throughput

0.458

High

1389826

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

0

High-throughput

0.458

High

279066

TRIM3
Tripartite motif-containing protein 3

1

4

High-throughput

0.445

High

124088

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.426

High

186344

RA51B
DNA repair protein RAD51 homolog 2

1

0

High-throughput

0.426

High

291693

XRP2
Protein XRP2

1

0

High-throughput

0.426

High

1047240

ATP7A
Copper-transporting ATPase 1

1

0

Small-scale

0.426

High

1203436

Q5BKU8
SYNE1 protein

1

7

High-throughput

0.417

High

1389783

BORC6
BLOC-1-related complex subunit 6

5

0

High-throughput

0.371

High

1013529

COG7
Conserved oligomeric Golgi complex subunit 7

4

0

High-throughput

0.360

High

1389784

VPS50
Syndetin

4

0

High-throughput

0.360

High

1389789

KXDL1
KxDL motif-containing protein 1

4

0

High-throughput

0.360

High

1117037

LAMC2
Laminin subunit gamma-2

3

0

High-throughput

0.347

High

1200058

EIPR1
EARP and GARP complex-interacting protein 1

3

0

High-throughput

0.347

High

1389782

BORC8
BLOC-1-related complex subunit 8

3

0

High-throughput

0.347

High

1389811

SNX7
Sorting nexin-7

3

0

High-throughput

0.347

High

1389820

COG6
Conserved oligomeric Golgi complex subunit 6

3

0

High-throughput

0.347

High

1389821

WASC3
WASH complex subunit 3

2

0

High-throughput

0.335

High

1211912

AKND1
Protein AKNAD1

2

0

High-throughput

0.324

High

1278553

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

0

High-throughput

0.299

High

326769

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

1144722

PWP2
Periodic tryptophan protein 2 homolog

1

0

High-throughput

0.279

Low

1242085

TTC27
Tetratricopeptide repeat protein 27

1

0

High-throughput

0.279

Low

1286401

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.279

Low

1230862

BICRL
BRD4-interacting chromatin-remodeling complex-associated protein-like

1

0

High-throughput

0.265

Low

1256456

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.265

Low

593604

GDC
Solute carrier family 25 member 16

1

0

High-throughput

0.249

Low

516711

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low

1167099

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1205203

NHSL2
NHS-like protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025