Interactor 1: EXOS3 (Q8IPX7)
Exosome complex component RRP40 (Ribosomal RNA-processing protein 40)
Gene: Rrp40

Interactor 2: EXOSX (Q9VFF3)
Exosome complex component 10 homolog (RRP6/EXOSC10) (EC 3.1.13.-)
Gene: Rrp6

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 38944040
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_A_exo1~RRP40_S1
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005730 - nucleolus
GO:0010468 - regulation of gene expression
GO:0071035 - nuclear polyadenylation-dependent rRNA catabolic process
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 232
Dm

1 900
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025