HitPredict

Interactor 1: NPAS2 (Q99743)
Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Basic-helix-loop-helix-PAS protein MOP4) (Class E basic helix-loop-helix protein 9) (bHLHe9) (Member of PAS protein 4) (PAS domain-containing protein 4)
Gene: NPAS2

Interactor 2: TRAF4 (Q9BUZ4)
TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83)
Gene: TRAF4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	16969126
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 470
+	Hs
		126126 BMAL1_HUMAN (2-480): 6.13e-113: 359: 23.17		TRAF2_HUMAN (2-465): 4.35e-117: 354: 29.86
+	Hs
		1313397 X5DP31_HUMAN (2-540): 7.56e-109: 349: 19.76		TRAF4_HUMAN (1-470): 5.03e-120: 361: 100.00
+	Hs
		1021012 X5DP31_HUMAN (2-540): 7.56e-109: 349: 19.76		TRAF2_HUMAN (2-465): 4.35e-117: 354: 29.86
+	Hs
		1313361 ARNT2_HUMAN (2-624): 3.56e-100: 328: 19.22		TRAF4_HUMAN (1-470): 5.03e-120: 361: 100.00
+	Hs
		1313395 X5D7T2_HUMAN (2-610): 7.17e-100: 326: 19.33		TRAF4_HUMAN (1-470): 5.03e-120: 361: 100.00
+	Hs
		1020939 ARNT2_HUMAN (2-624): 3.56e-100: 328: 19.22		TRAF2_HUMAN (2-465): 4.35e-117: 354: 29.86
+	Hs
		1085735 HIF1A_HUMAN (2-798): 6.81e-126: 399: 16.22		TRAF6_HUMAN (3-464): 1.61e-84: 271: 24.79
+	Hs
		1313396 X5D9H9_HUMAN (2-241): 2.72e-70: 238: 24.55		TRAF4_HUMAN (1-470): 5.03e-120: 361: 100.00
+	Hs
		301839 HIF1A_HUMAN (2-798): 6.81e-126: 399: 16.22		TRI37_HUMAN (5-465): 5.48e-55: 199: 13.81
+	Hs
		1023850 X5DP31_HUMAN (2-540): 7.56e-109: 349: 19.76		TRAF1_HUMAN (16-465): 6.07e-72: 235: 24.18
+	Hs
		1023805 ARNT2_HUMAN (2-624): 3.56e-100: 328: 19.22		TRAF1_HUMAN (16-465): 6.07e-72: 235: 24.18
+	Hs
		584973 HIF1A_HUMAN (2-798): 6.81e-126: 399: 16.22		RO52_HUMAN (9-286): 3.93e-44: 163: 14.84
+	Hs
		302072 X5DP31_HUMAN (2-540): 7.56e-109: 349: 19.76		TRI37_HUMAN (5-465): 5.48e-55: 199: 13.81
+	Hs
		302010 ARNT2_HUMAN (2-624): 3.56e-100: 328: 19.22		TRI37_HUMAN (5-465): 5.48e-55: 199: 13.81
+	Hs
		584971 NCOA1_HUMAN (15-186): 1.58e-09: 63.9: 29.73		RO52_HUMAN (9-286): 3.93e-44: 163: 14.84