Protein: GPX1
Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) (Phospholipid-hydroperoxide glutathione peroxidase GPX1) (EC 1.11.1.12)

Gene: GPX1
Organism: Homo sapiens
Interactions: 62
UniProt ID: P07203

Gene Ontology (top 5):
GO:0001659 - temperature homeostasis
GO:0001885 - endothelial cell development
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus
GO:0004602 - glutathione peroxidase activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

362125

ABL1
Tyrosine-protein kinase ABL1

1

1

Small-scale

0.586

High

451603

ABL2
Tyrosine-protein kinase ABL2

1

1

Small-scale

0.578

High

451614

RHGBB
Inactive Rho GTPase-activating protein 11B

2

0

High-throughput

0.547

High

451608

SBP1
Methanethiol oxidase

1

0

Small-scale

0.537

High

451601

IBP5
Insulin-like growth factor-binding protein 5

1

2

High-throughput

0.536

High

451606

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.536

High

451615

SP6
Transcription factor Sp6

1

1

High-throughput

0.536

High

451623

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

451634

PAXX
Protein PAXX

1

1

High-throughput

0.536

High

451642

CLIC5
Chloride intracellular channel protein 5

1

3

High-throughput

0.536

High

451648

HBS1L
HBS1-like protein

1

1

High-throughput

0.536

High

451597

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

451645

VAX2
Ventral anterior homeobox 2

1

1

High-throughput

0.515

High

451604

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.513

High

451617

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

451618

AAGAB
Alpha- and gamma-adaptin-binding protein p34

1

0

High-throughput

0.513

High

451622

TCAM1
TIR domain-containing adapter molecule 1

1

0

High-throughput

0.513

High

451625

TENS4
Tensin-4

1

0

High-throughput

0.513

High

451630

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

0

High-throughput

0.513

High

451636

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.513

High

451599

HXB6
Homeobox protein Hox-B6

1

1

High-throughput

0.489

High

451631

DNJB3
DnaJ homolog subfamily B member 3

1

2

High-throughput

0.489

High

451613

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.486

High

451624

FAM9B
Protein FAM9B

1

1

High-throughput

0.481

High

451602

PUR8
Adenylosuccinate lyase

1

2

High-throughput

0.479

High

451620

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

451628

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

1

High-throughput

0.479

High

451637

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

3

Small-scale

0.479

High

451639

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

451643

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

451611

FGL2
Fibroleukin

1

2

High-throughput

0.470

High

169900

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

324081

CE152
Centrosomal protein of 152 kDa

1

0

High-throughput

0.458

High

451610

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

451612

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

451616

FTM
Protein fantom

1

0

High-throughput

0.458

High

451629

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

451633

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

451640

CPAP
Centrosomal P4.1-associated protein

1

0

High-throughput

0.458

High

451641

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.458

High

451647

CE164
Centrosomal protein of 164 kDa

1

0

High-throughput

0.458

High

451619

TMIG1
Transmembrane and immunoglobulin domain-containing protein 1

1

1

Small-scale

0.445

High

214485

HXA2
Homeobox protein Hox-A2

1

1

High-throughput

0.437

High

451609

TIF1B
Transcription intermediary factor 1-beta

1

3

Small-scale

0.437

High

451646

TRI33
E3 ubiquitin-protein ligase TRIM33

1

3

High-throughput

0.437

High

166485

BACH1
Transcription regulator protein BACH1

1

0

High-throughput

0.426

High

404623

PRIO
Major prion protein

1

0

High-throughput

0.426

High

451626

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

451650

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.426

High

64170

ARG35
Rho guanine nucleotide exchange factor 35

1

1

High-throughput

0.407

High

451600

IBP4
Insulin-like growth factor-binding protein 4

1

2

High-throughput

0.407

High

451635

HIRP3
HIRA-interacting protein 3

1

1

High-throughput

0.407

High

451598

YJU2B
Probable splicing factor YJU2B

1

0

High-throughput

0.279

Low

451607

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

0

High-throughput

0.279

Low

451627

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

1

0

High-throughput

0.279

Low

451632

ZN414
Zinc finger protein 414

1

0

High-throughput

0.279

Low

451638

LIME1
Lck-interacting transmembrane adapter 1

1

0

High-throughput

0.279

Low

451649

SALL2
Sal-like protein 2

1

0

High-throughput

0.279

Low

105136

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

451605

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

451621

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.249

Low

451644

KLF15
Krueppel-like factor 15

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025