HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: PSD10 (O75832)
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))
Gene: PSMD10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	33961781, 26496610, 28539385, 28821611, 19412159, 35530310, 19615732, 17323924
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 226
+	Hs
		131047 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		EHMT2_HUMAN (6-142): 8.24e-41: 150: 29.20
+	Hs
		1253352 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		FANK1_HUMAN (1-194): 1.83e-53: 176: 22.96
+	Hs
		130653 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		MYPT2_HUMAN (6-92): 8.48e-11: 62.8: 20.69
+	Hs
		862087 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		DAPK1_HUMAN (2-100): 2.89e-20: 90.8: 17.17
+	Hs
		276156 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		PSD10_HUMAN (1-226): 8.43e-70: 214: 100.00
+	Hs
		161426 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		MYPT1_HUMAN (146-226): 1.06e-18: 85.9: 30.86
+	Sc
		797476 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		PSD10_YEAST (76-219): 1.91e-09: 57.8: 32.90
+	Hs
		317774 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		RAI14_HUMAN (1-109): 2.71e-20: 90.8: 23.85
+	Sc
		837213 RPN8_YEAST (29-185): 1.1e-11: 66.7: 26.38		PSD10_YEAST (76-219): 1.91e-09: 57.8: 32.90