HitPredict

Interactor 1: ARI3A (Q99856)
AT-rich interactive domain-containing protein 3A (ARID domain-containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (Dead ringer-like protein 1) (E2F-binding protein 1)
Gene: ARID3A

Interactor 2: NANOG (Q9H9S0)
Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog)
Gene: NANOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26687479
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 593 Hs			1 305
+	Hs
		641541 ARI3A_HUMAN (1-593): 5.33e-127: 387: 100.00		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679162 ARI3A_HUMAN (1-593): 5.33e-127: 387: 100.00		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		213373 ARI3A_HUMAN (1-593): 5.33e-127: 387: 100.00		TLX2_HUMAN (76-157): 1.26e-27: 110: 37.35
+	Hs
		211944 ARI3A_HUMAN (1-593): 5.33e-127: 387: 100.00		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		1218101 ARI3B_HUMAN (178-588): 1.08e-77: 258: 44.73		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		1244304 ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Dm
		950077 KDM5_DROME (31-462): 1.54e-77: 270: 13.65		UBX_DROME (10-161): 2.44e-34: 130: 22.37
+	Mm
		1194731 ARI3B_MOUSE (179-588): 1.11e-75: 253: 43.41		NANOG_MOUSE (1-303): 7.62e-40: 143: 54.98
+	Hs
		641471 ARI3B_HUMAN (178-588): 1.08e-77: 258: 44.73		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679135 ARI3B_HUMAN (178-588): 1.08e-77: 258: 44.73		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		211910 ARI3B_HUMAN (178-588): 1.08e-77: 258: 44.73		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		595646 KDM5B_HUMAN (160-458): 2.38e-62: 225: 16.18		HXA5_HUMAN (2-165): 8.34e-36: 131: 20.69
+	Hs
		641483 ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679138 ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		146160 ARI1A_HUMAN (42-571): 1.89e-59: 217: 16.15		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		213359 ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80		TLX2_HUMAN (76-157): 1.26e-27: 110: 37.35
+	Hs
		146163 ARI1A_HUMAN (42-571): 1.89e-59: 217: 16.15		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		211921 ARI1B_HUMAN (19-552): 1.33e-62: 226: 18.80		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		146119 ARI1A_HUMAN (42-571): 1.89e-59: 217: 16.15		TLX2_HUMAN (76-157): 1.26e-27: 110: 37.35
+	Hs
		146118 ARI1A_HUMAN (42-571): 1.89e-59: 217: 16.15		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86