Protein: INAR1
Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1)

Gene: INAR1, IFNAR1
Organism: Homo sapiens
Interactions: 68
UniProt ID: P17181

Gene Ontology (top 5):
GO:0004905 - type I interferon receptor activity
GO:0005764 - lysosome
GO:0005770 - late endosome
GO:0005886 - plasma membrane
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

378359

IFNB
Interferon beta

4

8

Small-scale

0.887

High

602882

INAR2
Interferon alpha/beta receptor 2

3

2

Small-scale

0.827

High

602867

TYK2
Non-receptor tyrosine-protein kinase TYK2

13

20

Small-scale

0.759

High

602884

STAT2
Signal transducer and activator of transcription 2

7

15

Small-scale

0.745

High

378249

IFNA2
Interferon alpha-2

2

8

Small-scale

0.719

High

582131

INGR1
Interferon gamma receptor 1

1

15

High-throughput

0.691

High

596452

CTLA4
Cytotoxic T-lymphocyte protein 4

1

5

High-throughput

0.691

High

602880

NOTC1
Neurogenic locus notch homolog protein 1

1

9

High-throughput

0.691

High

602908

FBW1B
F-box/WD repeat-containing protein 11

4

4

Small-scale

0.649

High

602909

FBW1A
F-box/WD repeat-containing protein 1A

4

4

Small-scale

0.633

High

602862

JAK1
Tyrosine-protein kinase JAK1

2

20

Small-scale

0.619

High

602870

IFNA8
Interferon alpha-8

1

8

Small-scale

0.618

High

602875

BMR1A
Bone morphogenetic protein receptor type-1A

2

15

High-throughput

0.611

High

602896

LAP4B
Lysosomal-associated transmembrane protein 4B

2

1

High-throughput

0.606

High

602892

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

19

High-throughput

0.601

High

602899

AP2M1
AP-2 complex subunit mu

2

0

Small-scale

0.576

High

193203

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.563

High

602868

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

1

Small-scale

0.561

High

602905

KPCD2
Serine/threonine-protein kinase D2

1

2

Small-scale

0.561

High

127632

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

5

High-throughput

0.536

High

163237

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

8

High-throughput

0.536

High

225929

STX6
Syntaxin-6

1

1

High-throughput

0.536

High

480688

LEG1
Galectin-1

1

19

High-throughput

0.536

High

532043

KIT
Mast/stem cell growth factor receptor Kit

1

11

High-throughput

0.536

High

541321

FGFR1
Fibroblast growth factor receptor 1

1

16

High-throughput

0.536

High

602860

FGFR2
Fibroblast growth factor receptor 2

1

17

High-throughput

0.536

High

602863

AVR2A
Activin receptor type-2A

1

15

High-throughput

0.536

High

602895

LRP10
Low-density lipoprotein receptor-related protein 10

1

6

High-throughput

0.536

High

602898

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

5

High-throughput

0.536

High

602911

LRP12
Low-density lipoprotein receptor-related protein 12

1

7

High-throughput

0.536

High

602902

ANM1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.523

High

602879

STAT6
Signal transducer and activator of transcription 6

1

15

Small-scale

0.515

High

602885

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.513

High

602897

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

Small-scale

0.512

High

602878

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

15

Small-scale

0.500

High

602864

CALX
Calnexin

1

7

High-throughput

0.489

High

602903

NFIP1
NEDD4 family-interacting protein 1

1

2

High-throughput

0.489

High

362722

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

410597

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.479

High

602865

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

Small-scale

0.479

High

602866

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

19

Small-scale

0.479

High

602874

BASI
Basigin

1

16

High-throughput

0.479

High

602877

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.479

High

602891

TRAF2
TNF receptor-associated factor 2

1

10

Small-scale

0.470

High

532343

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.458

High

602906

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

602881

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

3

Small-scale

0.457

High

602888

RACK1
Small ribosomal subunit protein RACK1

1

2

Small-scale

0.457

High

388366

B3AT
Band 3 anion transport protein

1

4

High-throughput

0.445

High

602876

TGFR2
TGF-beta receptor type-2

1

15

High-throughput

0.445

High

602883

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

Small-scale

0.445

High

602893

MK14
Mitogen-activated protein kinase 14

1

5

Small-scale

0.445

High

602894

NIPA1
Magnesium transporter NIPA1

1

5

High-throughput

0.445

High

602910

S27A6
Long-chain fatty acid transport protein 6

1

1

High-throughput

0.445

High

602869

1433B
14-3-3 protein beta/alpha

1

3

Small-scale

0.437

High

602871

GLYC
Serine hydroxymethyltransferase, cytosolic

1

2

Small-scale

0.437

High

602872

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

2

Small-scale

0.437

High

602886

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

2

Small-scale

0.437

High

602889

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

9

Small-scale

0.437

High

602890

EP300
Histone acetyltransferase p300

1

6

Small-scale

0.437

High

602907

TRI10
Tripartite motif-containing protein 10

1

5

Small-scale

0.437

High

602901

MF14A
Hippocampus abundant transcript 1 protein

1

7

High-throughput

0.407

High

602873

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

602900

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.279

Low

602904

PAXX
Protein PAXX

1

0

High-throughput

0.279

Low

572978

KPYM
Pyruvate kinase PKM

1

0

Small-scale

0.249

Low

602861

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

Small-scale

0.249

Low

602887

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025