Protein: INLR1
Interferon lambda receptor 1 (IFN-lambda receptor 1) (IFN-lambda-R1) (Cytokine receptor class-II member 12) (Cytokine receptor family 2 member 12) (CRF2-12) (Interleukin-28 receptor subunit alpha) (IL-28 receptor subunit alpha) (IL-28R-alpha) (IL-28RA) (Likely interleukin or cytokine receptor 2) (LICR2)

Gene: INLR1, IFNLR1
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q8IU57

Gene Ontology (top 5):
GO:0002385 - mucosal immune response
GO:0004896 - cytokine receptor activity
GO:0005886 - plasma membrane
GO:0008285 - negative regulation of cell population proliferation
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1306880

HMR1
Major histocompatibility complex class I-related protein 1

1

2

High-throughput

0.691

High

658731

JAK1
Tyrosine-protein kinase JAK1

3

16

Small-scale

0.673

High

1306871

IFNL1
Interferon lambda-1

1

0

Small-scale

0.614

High

1195533

CTXN3
Cortexin-3

2

1

High-throughput

0.606

High

1245875

BRID5
BRICHOS domain-containing protein 5

2

1

High-throughput

0.606

High

1292104

ANR46
Ankyrin repeat domain-containing protein 46

2

0

High-throughput

0.580

High

1306884

RANB9
Ran-binding protein 9

1

1

Small-scale

0.561

High

295750

AP1G2
AP-1 complex subunit gamma-like 2

1

1

High-throughput

0.536

High

931260

AT12A
Potassium-transporting ATPase alpha chain 2

1

1

High-throughput

0.536

High

956930

CXCR4
C-X-C chemokine receptor type 4

1

1

High-throughput

0.536

High

1111506

MTR1L
Melatonin-related receptor

1

3

High-throughput

0.536

High

1306875

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

2

High-throughput

0.536

High

504745

FBSP1
F-box/SPRY domain-containing protein 1

1

3

Small-scale

0.515

High

895258

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.513

High

1032610

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.513

High

1179660

D19L1
Protein C-mannosyl-transferase DPY19L1

1

0

High-throughput

0.513

High

1306874

T183A
Transmembrane protein 183A

1

0

High-throughput

0.513

High

1306886

OSBL8
Oxysterol-binding protein-related protein 8

1

0

High-throughput

0.513

High

989038

AP2B1
AP-2 complex subunit beta

1

1

High-throughput

0.501

High

299880

C1QRF
C1q-related factor

1

3

High-throughput

0.489

High

1253849

SRCAP
Helicase SRCAP

1

1

High-throughput

0.489

High

1295780

C1QL4
Complement C1q-like protein 4

1

3

High-throughput

0.489

High

1306887

TMX4
Thioredoxin-related transmembrane protein 4

1

2

High-throughput

0.489

High

1306888

TMX1
Thioredoxin-related transmembrane protein 1

1

2

High-throughput

0.489

High

1306891

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.489

High

1306892

FBW1B
F-box/WD repeat-containing protein 11

1

4

High-throughput

0.489

High

1306893

FBW1A
F-box/WD repeat-containing protein 1A

1

4

High-throughput

0.489

High

799271

BRCA1
Breast cancer type 1 susceptibility protein

1

3

Small-scale

0.479

High

1306894

TRAF6
TNF receptor-associated factor 6

1

5

Small-scale

0.479

High

1306889

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

0

Small-scale

0.458

High

714630

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

12

High-throughput

0.445

High

1306885

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

1

High-throughput

0.445

High

623419

RO52
E3 ubiquitin-protein ligase TRIM21

1

3

Small-scale

0.437

High

1100091

TIF1B
Transcription intermediary factor 1-beta

1

3

Small-scale

0.437

High

1125149

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

7

Small-scale

0.437

High

1306877

RNF10
E3 ubiquitin-protein ligase RNF10

1

1

Small-scale

0.437

High

1306879

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

Small-scale

0.437

High

482255

PAEP
Glycodelin

2

0

High-throughput

0.316

High

170221

AURKA
Aurora kinase A

1

0

High-throughput

0.279

Low

337765

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.279

Low

1306876

SRBD1
S1 RNA-binding domain-containing protein 1

1

0

High-throughput

0.279

Low

1306878

FAM3C
Protein FAM3C

1

0

High-throughput

0.279

Low

1306881

TTC28
Tetratricopeptide repeat protein 28

1

0

High-throughput

0.279

Low

1306882

TMM18
Transmembrane protein 18

1

0

High-throughput

0.279

Low

344556

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

0

High-throughput

0.265

Low

1258054

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

1288521

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

Small-scale

0.249

Low

1306883

ZFP91
E3 ubiquitin-protein ligase ZFP91

1

0

Small-scale

0.249

Low

1306890

AFF4
AF4/FMR2 family member 4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025