HitPredict

Interactor 1: SH3G2 (Q99962)
Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2)
Gene: SH3GL2

Interactor 2: SH3G2 (Q99962)
Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2)
Gene: SH3GL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 16115810, 20404169, 25517094
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BAR~BAR, SH3_2~SH3_2
Common GO terms GO:0000139 - Golgi membrane
GO:0001933 - negative regulation of protein phosphorylation
GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005829 - cytosol
and 15 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 352
Hs

1 352
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Last updated: 15 Jul 2024