HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	26169395, 28821611, 35530310
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... GO:0070628 - proteasome binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 1132
+	Hs
		176966 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		BAG6_HUMAN (1-1132): 0: 597: 100.00
+	Hs
		803427 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		BAG6_HUMAN (1-1132): 0: 597: 100.00
+	Dm
		1358677 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VWD9_DROME (9-531): 2.99e-29: 125: 13.66
+	Zm
		27878 B4FLQ8_MAIZE (1-309): 4.83e-111: 326: 79.29		A0A1D6JMS0_MAIZE (1-503): 1.51e-26: 117: 15.13
+	Hs
		131100 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71
+	Hs
		131091 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL4_HUMAN (6-549): 7.75e-26: 115: 11.19
+	Hs
		131106 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL1_HUMAN (15-521): 2.36e-25: 114: 12.84
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72
+	Hs
		130838 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RL40_HUMAN (17-87): 9.53e-28: 111: 34.72
+	Hs
		131125 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PCLO_HUMAN (238-807): 3.17e-17: 90.2: 11.32
+	Sc
		797465 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DSK2_YEAST (16-332): 1.34e-26: 115: 20.06
+	Zm
		46881 A0A3L6GBJ0_MAIZE (8-304): 3.94e-71: 226: 18.33		C0PFA7_MAIZE (19-249): 5.16e-28: 122: 22.85
+	Dm
		640796 PSMD7_DROME (27-185): 4.64e-35: 131: 23.03		Q9VWD9_DROME (9-531): 2.99e-29: 125: 13.66
+	Hs
		849280 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71
+	Hs
		849284 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL1_HUMAN (15-521): 2.36e-25: 114: 12.84