HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	35530310, 19013454
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... GO:0070628 - proteasome binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Hs			1 363
+	Rn
		1117318 Q4V8E2_RAT (1-310): 1.28e-110: 324: 100.00		RD23B_RAT (3-363): 6.38e-109: 326: 52.05
+	Hs
		130814 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03
+	Sc
		697094 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		RAD23_YEAST (3-361): 1e-75: 240: 28.57
+	Hs
		131106 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47
+	Hs
		131100 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08
+	Hs
		131091 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL4_HUMAN (3-312): 3.05e-45: 165: 15.57
+	Hs
		849167 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		RD23A_HUMAN (1-363): 4.01e-119: 350: 100.00
+	Hs
		130790 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		BAG6_HUMAN (2-307): 5.25e-38: 146: 15.22
+	Hs
		130838 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RL40_HUMAN (3-129): 1.37e-38: 136: 22.84
+	Hs
		849168 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03
+	Hs
		130704 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBB_HUMAN (3-81): 4.96e-28: 111: 30.38
+	Sc
		797465 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DSK2_YEAST (1-246): 3.36e-35: 134: 20.65
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (3-93): 2.9e-16: 77.1: 27.47
+	Zm
		46881 A0A3L6GBJ0_MAIZE (8-304): 3.94e-71: 226: 18.33		C0PFA7_MAIZE (4-311): 8.88e-44: 161: 13.64
+	Hs
		176966 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		BAG6_HUMAN (2-307): 5.25e-38: 146: 15.22
+	Hs
		849284 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47
+	Hs
		803427 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		BAG6_HUMAN (2-307): 5.25e-38: 146: 15.22
+	Hs
		849280 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL2_HUMAN (2-312): 1.85e-45: 166: 16.08
+	Hs
		317702 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		UBB_HUMAN (3-81): 4.96e-28: 111: 30.38
+	Hs
		474952 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		UBB_HUMAN (3-81): 4.96e-28: 111: 30.38