HitPredict

Interactor 1: RFXAP (O00287)
Regulatory factor X-associated protein (RFX-associated protein) (RFX DNA-binding complex 36 kDa subunit)
Gene: RFXAP

Interactor 2: RFXK (O14593)
DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: RFXANK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.741

Property	Details
Experiments	25752541, 11463838, 33961781, 10825209, 10938133, unassigned3799
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0045348 - positive regulation of MHC class II biosynthetic process GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 260
+	Hs
		130882 RFXAP_HUMAN (1-272): 1.74e-156: 438: 100.00		ANRA2_HUMAN (34-252): 4.83e-73: 227: 57.27