Protein: TIM
Protein timeless homolog (hTIM)

Gene: TIM, TIMELESS
Organism: Homo sapiens
Interactions: 70
UniProt ID: Q9UNS1

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0000785 - chromatin
GO:0002009 - morphogenesis of an epithelium
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1314300

TIPIN
TIMELESS-interacting protein

9

4

Small-scale

0.753

High

709112

MCM7
DNA replication licensing factor MCM7

4

8

Small-scale

0.694

High

996960

SSRP1
FACT complex subunit SSRP1

3

1

High-throughput

0.675

High

627393

MCM3
DNA replication licensing factor MCM3

3

10

Small-scale

0.667

High

1335005

CLSPN
Claspin

3

1

Small-scale

0.664

High

1310754

PSF3
DNA replication complex GINS protein PSF3

3

0

High-throughput

0.638

High

555692

H2AX
Histone H2AX

2

1

High-throughput

0.628

High

456000

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.618

High

652606

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

1

Small-scale

0.611

High

832779

MCM2
DNA replication licensing factor MCM2

2

8

Small-scale

0.611

High

952700

H33
Histone H3.3

2

1

High-throughput

0.611

High

1189045

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.586

High

554056

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.585

High

721780

RFA3
Replication protein A 14 kDa subunit

2

0

Small-scale

0.585

High

1263418

ATRIP
ATR-interacting protein

2

0

Small-scale

0.585

High

935371

H31
Histone H3.1

2

1

High-throughput

0.584

High

861982

PLK1
Serine/threonine-protein kinase PLK1

1

1

Small-scale

0.561

High

264250

CDC45
Cell division control protein 45 homolog

1

1

High-throughput

0.536

High

957961

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

900088

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.518

High

1239658

ZSCA1
Zinc finger and SCAN domain-containing protein 1

1

0

High-throughput

0.518

High

1115768

CRY2
Cryptochrome-2

1

2

Small-scale

0.515

High

71277

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.513

High

362311

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

454777

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

851743

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.513

High

1224921

FAM9B
Protein FAM9B

1

0

High-throughput

0.513

High

1231262

H2B3B
Histone H2B type 3-B

1

0

High-throughput

0.513

High

1297513

PRIPO
DNA-directed primase/polymerase protein

1

0

Small-scale

0.513

High

154268

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.493

High

172284

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

1306453

CML1
Chemerin-like receptor 1

1

1

High-throughput

0.489

High

160856

AURKA
Aurora kinase A

1

1

Small-scale

0.479

High

391968

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.479

High

708801

MCM5
DNA replication licensing factor MCM5

1

9

Small-scale

0.479

High

1044272

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.479

High

1221836

SMC5
Structural maintenance of chromosomes protein 5

1

2

Small-scale

0.479

High

1291072

DDX11
ATP-dependent DNA helicase DDX11

1

1

Small-scale

0.479

High

1292296

AURKB
Aurora kinase B

1

1

Small-scale

0.479

High

1302143

SMC6
Structural maintenance of chromosomes protein 6

1

3

Small-scale

0.479

High

206169

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

274394

WDHD1
WD repeat and HMG-box DNA-binding protein 1

1

0

Small-scale

0.458

High

295407

RECQ4
ATP-dependent DNA helicase Q4

1

0

Small-scale

0.458

High

385720

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

415104

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.458

High

435190

SP1
Transcription factor Sp1

1

0

Small-scale

0.458

High

517541

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

941583

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

963703

E2F1
Transcription factor E2F1

1

0

Small-scale

0.458

High

1030025

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1284401

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

1348592

DONS
Protein downstream neighbor of Son

1

0

Small-scale

0.458

High

1348914

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

856494

EFNA4
Ephrin-A4

1

1

High-throughput

0.437

High

1038192

ATR
Serine/threonine-protein kinase ATR

1

0

Small-scale

0.426

High

702320

CD70
CD70 antigen

2

0

High-throughput

0.328

High

879446

FCGRN
IgG receptor FcRn large subunit p51

2

0

High-throughput

0.328

High

1204535

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

0

High-throughput

0.328

High

1255549

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

2

0

High-throughput

0.318

High

196895

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.279

Low

957510

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1031117

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1136856

FAXC
Failed axon connections homolog

1

0

High-throughput

0.279

Low

1252981

TBC16
TBC1 domain family member 16

1

0

High-throughput

0.279

Low

1292001

BSCL2
Seipin

1

0

High-throughput

0.279

Low

1356216

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

364627

TRFE
Serotransferrin

1

0

High-throughput

0.251

Low

1166069

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1172271

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1331630

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024