Interactor 1: ECSIT (Q9BQ95)
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)
Gene: ECSIT

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 29929436, 31281713, 25371197
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0034142 - toll-like receptor 4 signaling pathway
GO:0045087 - innate immune response
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 431
Hs

1 522
+ Mm
+ Dm
+ Dm

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Last updated: 15 Jul 2024