Protein: PPM1L
Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon)

Gene: PPM1L
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q5SGD2

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0007165 - signal transduction
GO:0007178 - cell surface receptor protein serine/threonine kinase signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

213944

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

7

Small-scale

0.561

High

484159

PGFRB
Platelet-derived growth factor receptor beta

1

8

High-throughput

0.541

High

219309

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.513

High

595056

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

0

High-throughput

0.513

High

1209926

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.513

High

1209928

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.513

High

710284

EPHA2
Ephrin type-A receptor 2

1

5

High-throughput

0.494

High

183935

S22A2
Solute carrier family 22 member 2

1

1

High-throughput

0.445

High

1197783

S39AC
Zinc transporter ZIP12

1

3

High-throughput

0.445

High

1209923

S39A4
Zinc transporter ZIP4

1

3

High-throughput

0.445

High

1209924

SL9A6
Sodium/hydrogen exchanger 6

1

3

High-throughput

0.445

High

1209925

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

0

High-throughput

0.426

High

1139445

S39AE
Metal cation symporter ZIP14

1

3

High-throughput

0.407

High

1194519

SL9C1
Solute carrier family 9 member C1

1

3

High-throughput

0.407

High

1209918

SL9C2
Sodium/hydrogen exchanger 11

1

3

High-throughput

0.407

High

1209922

TTC27
Tetratricopeptide repeat protein 27

1

3

High-throughput

0.407

High

1209929

TELO2
Telomere length regulation protein TEL2 homolog

1

1

High-throughput

0.407

High

771775

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

1209919

TDR10
Tudor domain-containing protein 10

1

0

High-throughput

0.279

Low

1209921

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.279

Low

1209927

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

133752

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.249

Low

218280

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

1209920

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025