HitPredict

Interactor 1: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Interactor 2: SYF1 (Q9HCS7)
Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2)
Gene: XAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 315 Hs			1 855
+	Hs
		209486 PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15		SYF1_HUMAN (1-855): 0: 602: 100.00
+	Hs
		1288323 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		SYF1_HUMAN (1-855): 0: 602: 100.00
+	Sp
		1319489 YN55_SCHPO (28-288): 7.99e-72: 225: 41.60		SYF1_SCHPO (21-772): 2.32e-148: 457: 43.65
+	Hs
		1310798 WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		209476 PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		1288293 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Sp
		953579 YN55_SCHPO (28-288): 7.99e-72: 225: 41.60		CLF1_SCHPO (471-778): 7.87e-33: 137: 13.61
+	Dm
		54179 Q9VYQ9_DROME (2-313): 9.5e-88: 272: 21.78		SYF1_DROME (1-255): 9.35e-16: 83.9: 13.69
+	Hs
		174768 WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		1022304 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		CSTF3_HUMAN (11-543): 2.99e-35: 145: 13.25
+	Hs
		300222 FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Dm
		571971 Q9VPL0_DROME (2-217): 1.78e-56: 187: 20.26		CRN_DROME (473-778): 5.65e-29: 125: 15.61
+	Hs
		903236 WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		300229 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		300095 WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		1058000 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		RRP5_HUMAN (11-347): 9.5e-18: 90.8: 11.26
+	Hs
		903230 WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60		RRP5_HUMAN (11-347): 9.5e-18: 90.8: 11.26
+	Sp
		224207 TUP11_SCHPO (134-315): 1.35e-42: 156: 19.69		CYC8_SCHPO (3-232): 7.02e-13: 74.7: 10.26
+	Hs
		1058048 NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54		RRP5_HUMAN (11-347): 9.5e-18: 90.8: 11.26
+	Sp
		224208 TUP12_SCHPO (142-312): 1.06e-35: 137: 17.03		CYC8_SCHPO (3-232): 7.02e-13: 74.7: 10.26