Protein: CUL9
Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein)

Gene: CUL9
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q8IWT3

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0007088 - regulation of mitotic nuclear division

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1134978

CUL7
Cullin-7

6

4

Small-scale

0.937

High

983877

RBX1
E3 ubiquitin-protein ligase RBX1

5

7

Small-scale

0.915

High

1310769

GLMN
Glomulin

4

1

High-throughput

0.892

High

995990

UB2L3
Ubiquitin-conjugating enzyme E2 L3

3

20

Small-scale

0.840

High

1310754

CUL9
Cullin-9

3

16

Small-scale

0.834

High

1310802

RBX2
RING-box protein 2

2

9

High-throughput

0.776

High

414164

P53
Cellular tumor antigen p53

21

10

Small-scale

0.766

High

507267

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

19

High-throughput

0.691

High

1310771

UBE2F
NEDD8-conjugating enzyme UBE2F

1

20

High-throughput

0.691

High

1310803

APEX2
DNA-(apurinic or apyrimidinic site) endonuclease 2

3

1

High-throughput

0.667

High

970219

UB2G1
Ubiquitin-conjugating enzyme E2 G1

1

20

Small-scale

0.647

High

1310797

RAB6B
Ras-related protein Rab-6B

2

8

High-throughput

0.628

High

1310822

TF3C3
General transcription factor 3C polypeptide 3

1

4

High-throughput

0.618

High

718592

CDC27
Cell division cycle protein 27 homolog

1

6

Small-scale

0.618

High

992247

SKP1
S-phase kinase-associated protein 1

1

3

High-throughput

0.618

High

1092998

CDC16
Cell division cycle protein 16 homolog

1

6

Small-scale

0.618

High

1113627

CUL3
Cullin-3

1

14

High-throughput

0.618

High

1154868

NEDD8
Ubiquitin-like protein NEDD8

1

7

High-throughput

0.618

High

1310807

CDC23
Cell division cycle protein 23 homolog

1

6

Small-scale

0.618

High

1310808

APC7
Anaphase-promoting complex subunit 7

1

6

Small-scale

0.618

High

1310811

ANC2
Anaphase-promoting complex subunit 2

1

14

Small-scale

0.618

High

1310810

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.586

High

507035

POTEJ
POTE ankyrin domain family member J

1

4

High-throughput

0.553

High

1063805

LG3BP
Galectin-3-binding protein

1

15

High-throughput

0.553

High

1023569

CYC
Cytochrome c

1

0

Small-scale

0.537

High

49569

FEZF1
Fez family zinc finger protein 1

1

20

High-throughput

0.536

High

188503

NVL
Nuclear valosin-containing protein-like

1

8

High-throughput

0.536

High

510049

ZN865
Zinc finger protein 865

1

6

High-throughput

0.536

High

711377

SHC1
SHC-transforming protein 1

1

7

High-throughput

0.536

High

713169

NOS1
Nitric oxide synthase 1

1

1

High-throughput

0.536

High

872505

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.536

High

948211

ZN445
Zinc finger protein 445

1

7

High-throughput

0.536

High

1044428

ZNF92
Zinc finger protein 92

1

3

High-throughput

0.536

High

1066059

ZN616
Zinc finger protein 616

1

6

High-throughput

0.536

High

1106489

GAB1
GRB2-associated-binding protein 1

1

1

High-throughput

0.536

High

1153639

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

15

High-throughput

0.536

High

1211694

FA83B
Protein FAM83B

1

3

High-throughput

0.536

High

1234773

ZN770
Zinc finger protein 770

1

6

High-throughput

0.536

High

1252575

ZN841
Zinc finger protein 841

1

6

High-throughput

0.536

High

1271962

ZN765
Zinc finger protein 765

1

9

High-throughput

0.536

High

1294039

ZN761
Zinc finger protein 761

1

7

High-throughput

0.536

High

1294344

ZN677
Zinc finger protein 677

1

7

High-throughput

0.536

High

1310756

ARRD1
Arrestin domain-containing protein 1

1

8

High-throughput

0.536

High

1310763

ZN397
Zinc finger protein 397

1

11

High-throughput

0.536

High

1310764

ZN480
Zinc finger protein 480

1

8

High-throughput

0.536

High

1310772

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

3

High-throughput

0.536

High

1310773

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

1310779

ZN845
Zinc finger protein 845

1

7

High-throughput

0.536

High

1310781

DPYL5
Dihydropyrimidinase-related protein 5

1

4

High-throughput

0.536

High

1310793

AGO4
Protein argonaute-4

1

4

High-throughput

0.536

High

1310801

ZN624
Zinc finger protein 624

1

6

High-throughput

0.536

High

1310806

ZN107
Zinc finger protein 107

1

6

High-throughput

0.536

High

1310821

MYO5A
Unconventional myosin-Va

1

3

High-throughput

0.536

High

829451

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

2

6

High-throughput

0.521

High

1310770

H2B1H
Histone H2B type 1-H

1

4

High-throughput

0.515

High

1219510

ANR22
Ankyrin repeat domain-containing protein 22

1

7

High-throughput

0.514

High

1310777

CDCA5
Sororin

1

0

High-throughput

0.513

High

1310783

MTNA
Methylthioribose-1-phosphate isomerase

1

0

High-throughput

0.513

High

249165

DSCAM
Cell adhesion molecule DSCAM

1

3

High-throughput

0.494

High

717110

ECHM
Enoyl-CoA hydratase, mitochondrial

1

7

High-throughput

0.489

High

908639

PRELP
Prolargin

1

2

High-throughput

0.489

High

1213032

CC183
Coiled-coil domain-containing protein 183

1

6

High-throughput

0.489

High

1257785

ACD11
Acyl-CoA dehydrogenase family member 11

1

2

High-throughput

0.489

High

1310757

TTC9C
Tetratricopeptide repeat protein 9C

1

8

High-throughput

0.489

High

123139

DX39A
ATP-dependent RNA helicase DDX39A

1

11

Small-scale

0.479

High

137542

NR5A2
Nuclear receptor subfamily 5 group A member 2

1

6

High-throughput

0.479

High

141562

DDX3X
ATP-dependent RNA helicase DDX3X

1

9

Small-scale

0.479

High

168719

CSKP
Peripheral plasma membrane protein CASK

1

8

High-throughput

0.479

High

174548

TRI66
Tripartite motif-containing protein 66

1

12

High-throughput

0.479

High

188693

BIRC5
Baculoviral IAP repeat-containing protein 5

1

5

Small-scale

0.479

High

257058

F262
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

1

2

High-throughput

0.479

High

272306

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.479

High

289606

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

13

Small-scale

0.479

High

408973

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.479

High

462503

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

16

Small-scale

0.479

High

557371

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

High-throughput

0.479

High

633741

PSB1
Proteasome subunit beta type-1

1

4

High-throughput

0.479

High

680938

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

807487

IF4A3
Eukaryotic initiation factor 4A-III

1

12

Small-scale

0.479

High

848795

MAGAA
Melanoma-associated antigen 10

1

3

High-throughput

0.479

High

889454

CLK1
Dual specificity protein kinase CLK1

1

4

High-throughput

0.479

High

890353

NU153
Nuclear pore complex protein Nup153

1

18

Small-scale

0.479

High

908299

AFF3
AF4/FMR2 family member 3

1

7

High-throughput

0.479

High

921944

COPA
Coatomer subunit alpha

1

5

Small-scale

0.479

High

922591

AP2S1
AP-2 complex subunit sigma

1

3

High-throughput

0.479

High

952597

MYL6
Myosin light polypeptide 6

1

5

High-throughput

0.479

High

995682

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.479

High

997835

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.479

High

1029512

SRSF2
Serine/arginine-rich splicing factor 2

1

13

High-throughput

0.479

High

1062539

DHX9
ATP-dependent RNA helicase A

1

6

Small-scale

0.479

High

1085896

TWF1
Twinfilin-1

1

3

High-throughput

0.479

High

1102012

PABP4
Polyadenylate-binding protein 4

1

11

Small-scale

0.479

High

1103891

MYO7A
Unconventional myosin-VIIa

1

4

High-throughput

0.479

High

1108597

TBB3
Tubulin beta-3 chain

1

12

High-throughput

0.479

High

1123970

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

Small-scale

0.479

High

1138375

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

Small-scale

0.479

High

1158798

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

2

High-throughput

0.479

High

1193340

GLYR1
Cytokine-like nuclear factor N-PAC

1

3

High-throughput

0.479

High

1218928

TASO2
Protein TASOR 2

1

10

High-throughput

0.479

High

1242013

SCYL2
SCY1-like protein 2

1

4

High-throughput

0.479

High

1245789

DOK6
Docking protein 6

1

1

High-throughput

0.479

High

1272174

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

1

High-throughput

0.479

High

1307479

MY18B
Unconventional myosin-XVIIIb

1

3

High-throughput

0.479

High

1310762

PPHLN
Periphilin-1

1

1

High-throughput

0.479

High

1310775

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

6

High-throughput

0.479

High

1310778

DOCK6
Dedicator of cytokinesis protein 6

1

3

High-throughput

0.479

High

1310786

KPCD2
Serine/threonine-protein kinase D2

1

7

High-throughput

0.479

High

1310788

IF5A2
Eukaryotic translation initiation factor 5A-2

1

2

High-throughput

0.479

High

1310790

CCDC8
Coiled-coil domain-containing protein 8

1

4

High-throughput

0.479

High

1310798

ATD3A
ATPase family AAA domain-containing protein 3A

1

12

High-throughput

0.479

High

1310804

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

1310805

HERC5
E3 ISG15--protein ligase HERC5

1

6

Small-scale

0.479

High

1310813

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

13

Small-scale

0.479

High

1310814

AGO1
Protein argonaute-1

1

4

High-throughput

0.479

High

448049

ITAV
Integrin alpha-V

1

0

High-throughput

0.458

High

1011657

RT35
Small ribosomal subunit protein mS35

1

0

High-throughput

0.458

High

1031112

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

0

Small-scale

0.458

High

1310758

TTLL6
Tubulin polyglutamylase TTLL6

1

0

High-throughput

0.458

High

1310791

APC1
Anaphase-promoting complex subunit 1

1

0

Small-scale

0.458

High

1310809

APC5
Anaphase-promoting complex subunit 5

1

0

Small-scale

0.458

High

1310818

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.458

High

1310820

RT16
Small ribosomal subunit protein bS16m

1

0

High-throughput

0.458

High

1063976

ECHP
Peroxisomal bifunctional enzyme

1

6

High-throughput

0.445

High

1290449

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

4

High-throughput

0.445

High

1310787

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

2

High-throughput

0.445

High

284693

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

3

High-throughput

0.437

High

369699

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.437

High

399594

VTNC
Vitronectin

1

4

High-throughput

0.437

High

522457

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.437

High

650847

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

20

Small-scale

0.437

High

787676

SPB5
Serpin B5

1

4

High-throughput

0.437

High

794534

RBMX
RNA-binding motif protein, X chromosome

1

15

Small-scale

0.437

High

813151

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.437

High

979946

H4
Histone H4

1

4

Small-scale

0.437

High

1011483

RT10
Small ribosomal subunit protein uS10m

1

2

High-throughput

0.437

High

1024401

S25A3
Solute carrier family 25 member 3

1

4

High-throughput

0.437

High

1217060

F222A
Protein FAM222A

1

2

High-throughput

0.437

High

1239450

H3C
Histone H3.3C

1

8

High-throughput

0.437

High

1241680

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

Small-scale

0.437

High

1295686

HORN
Hornerin

1

4

Small-scale

0.437

High

1310755

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

7

High-throughput

0.437

High

1310766

TAF4B
Transcription initiation factor TFIID subunit 4B

1

4

High-throughput

0.437

High

1310767

SEM4D
Semaphorin-4D

1

1

High-throughput

0.437

High

1310768

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

2

High-throughput

0.437

High

1310776

RT24
Small ribosomal subunit protein uS3m

1

2

High-throughput

0.437

High

1310780

LOXL4
Lysyl oxidase homolog 4

1

5

High-throughput

0.437

High

1310782

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.437

High

1310784

GTPB2
GTP-binding protein 2

1

8

High-throughput

0.437

High

1310789

BRD8
Bromodomain-containing protein 8

1

7

High-throughput

0.437

High

1310792

VPP4
V-type proton ATPase 116 kDa subunit a 4

1

1

High-throughput

0.437

High

1310795

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

1

High-throughput

0.437

High

1310796

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.437

High

1310799

SLTM
SAFB-like transcription modulator

1

11

High-throughput

0.437

High

1310812

RALY
RNA-binding protein Raly

1

6

High-throughput

0.437

High

1310815

PLXB3
Plexin-B3

1

3

Small-scale

0.417

High

638467

FPR1
fMet-Leu-Phe receptor

1

2

High-throughput

0.407

High

914447

EFNB2
Ephrin-B2

1

1

High-throughput

0.407

High

1310761

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

2

High-throughput

0.407

High

1310816

FZD10
Frizzled-10

1

2

High-throughput

0.407

High

1310800

SH3B4
SH3 domain-binding protein 4

2

0

High-throughput

0.318

High

1085774

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.279

Low

1215444

DEP1A
DEP domain-containing protein 1A

1

0

High-throughput

0.279

Low

1310785

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

1310794

JPH1
Junctophilin-1

1

0

High-throughput

0.279

Low

256327

RT14
Small ribosomal subunit protein uS14m

1

0

High-throughput

0.249

Low

612095

ITB5
Integrin beta-5

1

0

High-throughput

0.249

Low

963626

TGFB2
Transforming growth factor beta-2 proprotein

1

0

High-throughput

0.249

Low

1310759

TEX19
Testis-expressed protein 19

1

0

High-throughput

0.249

Low

1310765

CCNB3
G2/mitotic-specific cyclin-B3

1

0

High-throughput

0.249

Low

1310774

ISOC1
Isochorismatase domain-containing protein 1

1

0

High-throughput

0.249

Low

1310817

RT33
Small ribosomal subunit protein mS33

1

0

High-throughput

0.249

Low

1310819

RT28
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.249

Low

1185881

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.232

Low

1310760

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025