HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	35530310, 27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 624
+	Hs
		131106 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		1358677 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		131091 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Zm
		27878 B4FLQ8_MAIZE (1-309): 4.83e-111: 326: 79.29		A0A1D6JMS0_MAIZE (26-544): 2.17e-96: 307: 27.56
+	Hs
		849280 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		849284 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		640796 PSMD7_DROME (27-185): 4.64e-35: 131: 23.03		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Zm
		46881 A0A3L6GBJ0_MAIZE (8-304): 3.94e-71: 226: 18.33		C0PFA7_MAIZE (40-544): 1.68e-92: 298: 26.19
+	Hs
		130790 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		131017 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		130934 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		130838 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Sc
		797465 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		DSK2_YEAST (32-239): 1.13e-31: 128: 31.19
+	Hs
		176966 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		803427 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		849244 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		849216 PSMD7_HUMAN (28-185): 3.22e-34: 128: 22.56		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59